CAJ | 학술논문

13C是稳定性核素，其标记的诊断试剂已逐渐应用于临床，尤其是13C标记的尿素呼气实验，其被广泛用于胃幽门螺旋杆菌感染的诊断。13C标记的其他化合物如氨基比林、美沙西丁、辛酸、混合甘油三酯等还可用于消化系统中其他疾病的诊断。由于13C标记的诊断试剂具有无创、安全、无辐射的特点，其适用于儿童、孕妇等患者，已受到越来越多学者的关注，该文对近几年13C在消化系统疾病诊断方面的研究进展作一综述。
13C시은정성핵소，기표기적진단시제이축점응용우림상，우기시13C표기적뇨소호기실험，기피엄범용우위유문라선간균감염적진단。13C표기적기타화합물여안기비림、미사서정、신산、혼합감유삼지등환가용우소화계통중기타질병적진단。유우13C표기적진단시제구유무창、안전、무복사적특점，기괄용우인동、잉부등환자，이수도월래월다학자적관주，해문대근궤년13C재소화계통질병진단방면적연구진전작일종술。
13C is a stable nuclide and its labeled substrates have already used in clinic. Among the substrates, 13C-urea is the mainstream of clinical practice to diagnose the Helicobacter pylori. The other substrates such as aminopyrine, methacetin, octanoic and mixed triglyceride are used to diagnose dis-eases of the digestive system. Because the 13C-labeled compounds are non-invasive, safe, nonradiative and suitable for pregnant women and children, so many researchers focus on them. This paper makes a review on the research progress of 13C-labeled substrates in the diagnosis of digestive system disease in re-cent years.