CAJ | 학술논문

目的：分析18F-FDG PET/CT检查中出现棕色脂肪组织（BAT）摄取与室外温度之间的关系。方法回顾性分析上海长海医院核医学科20949例受检者的18F-FDG PET/CT图像，并通过PubMed查询2002至2013年间BAT摄取相关研究，收集对应检查日期的检查地区温度，使用一元线性回归分析模型分析 BAT摄取发生率（P）与平均室外温度（T）之间的关系。结果PubMed共查询到10项符合标准的相关研究，纳入本研究后（11项研究共44581例）经简单线性回归分析结果表明，BAT摄取发生率与室外温度呈显著负相关（r=-0.718，P=0.013），回归方程为P（%）=6.87-0.22×T（℃），每当气温上升5℃，BAT摄取发生率下降约1%。结论 BAT摄取发生率比较低，且与平均室外温度呈显著负相关关系。
목적：분석18F-FDG PET/CT검사중출현종색지방조직（BAT）섭취여실외온도지간적관계。방법회고성분석상해장해의원핵의학과20949례수검자적18F-FDG PET/CT도상，병통과PubMed사순2002지2013년간BAT섭취상관연구，수집대응검사일기적검사지구온도，사용일원선성회귀분석모형분석 BAT섭취발생솔（P）여평균실외온도（T）지간적관계。결과PubMed공사순도10항부합표준적상관연구，납입본연구후（11항연구공44581례）경간단선성회귀분석결과표명，BAT섭취발생솔여실외온도정현저부상관（r=-0.718，P=0.013），회귀방정위P（%）=6.87-0.22×T（℃），매당기온상승5℃，BAT섭취발생솔하강약1%。결론 BAT섭취발생솔비교저，차여평균실외온도정현저부상관관계。
Objective To investigate the association between the prevalence of activated brown adipose tissue ( BAT) and the average outdoor temperature in 18F-FDG PET/CT. Methods 18F-FDG PET/CT scans were performed in 20 949 cases in nuclear medicine department of Changhai hospital and BAT studies from PubMed (2002-2013) were reviewed, and the average outdoor temperatures during the study periods were obtained. A simple linear regression was used to analyze the association between the prevalence of activated BAT (P) and the average outdoor temperature (T). Results The review analysis for 11 BAT studies(n=44 581) (including 10 BAT studies from PubMed that meet the criteria for this study) showed a significant negative correlation(r=-0.718, P=0.013) between the prevalence of activat-ed BAT and the average outdoor temperature. The equation of the regression line is P(%)=6.87-0.22×T(℃). The prevalence of activated BAT decreased by about 1%for each 5 ℃increase in average outdoor tem-perature. Conclusion The prevalence of activated BAT is low in subtropics, there is a significant linear negative correlation between the prevalence of activated BAT and the average outdoor temperature.