CAJ | 학술논문

川崎病导致的心血管并发症目前已经成为儿童获得性心脏病的主要病因。尽管川崎病的诊治研究已经历了数十年，其具体病因仍不完全明确。部分川崎病患者对丙种球蛋白治疗没有反应，激素的应用目前仍然存在争议。临床中一些患者可出现严重的全身症状，甚至死亡。冠状动脉病变严重程度与预后判断并非易事。该文对近年来川崎病诊治中提出的新观点重点阐述。
천기병도치적심혈관병발증목전이경성위인동획득성심장병적주요병인。진관천기병적진치연구이경력료수십년，기구체병인잉불완전명학。부분천기병환자대병충구단백치료몰유반응，격소적응용목전잉연존재쟁의。림상중일사환자가출현엄중적전신증상，심지사망。관상동맥병변엄중정도여예후판단병비역사。해문대근년래천기병진치중제출적신관점중점천술。
Kawasaki disease has been the major etiology of aquired heart problems in children. Mecha-nisms of Kawasaki disease are still unclear in the past years. Some Kawasaki disease patients were not responsive to intravenous immunoglobulin therapy. And corticosteroid therapy remains controversial in the treatment of Ka-wasaki disease. A few patients with Kawasaki disease presented severe systemic symptoms,and even died for it. It is difficult to evaluate the severity of coronary artery lesions and prognosis of Kawasaki disease. In this article, we reviewed some new concepts on diagnosis and treatments on Kawasaki disease.