CAJ | 학술논문

目的：比较腹腔镜前列腺切除术（laparoscopic prostatectomy，LP）和开放前列腺切除术（Open Prostatectomy，OP）治疗大体积良性前列腺增生（Benign prostatic hyperplasia，BPH）的疗效和安全性。方法检索MedLine、Embase 比较 LP 和 OP 治疗大体积 BPH 的文献。采用 Revman5.0进行 Meta 分析。结果纳入文献3篇。术后 LP 组和 OP 组患者国际前列腺症状评分（International prostate symptom score，IPSS）、最大尿流率（maximum flow rate，Qmax）比较无统计学差异（P ＞0.05）。两组间手术时间、前列腺切除重量、术后留置尿管时间和住院时间、术中输血率比较，差异有统计学意义（P ＜0.05）。两组间尿道狭窄、尿失禁及二次手术发生率比较，差异无统计学意义（P ＞0.05）。结论LP 和 OP 对大体积前列腺 BPH 有相同的近期疗效。LP 组手术时间长、切除前列腺组织少，但是术后膀胱冲洗时间、留置尿管时间、住院时间短。
목적：비교복강경전렬선절제술（laparoscopic prostatectomy，LP）화개방전렬선절제술（Open Prostatectomy，OP）치료대체적량성전렬선증생（Benign prostatic hyperplasia，BPH）적료효화안전성。방법검색MedLine、Embase 비교 LP 화 OP 치료대체적 BPH 적문헌。채용 Revman5.0진행 Meta 분석。결과납입문헌3편。술후 LP 조화 OP 조환자국제전렬선증상평분（International prostate symptom score，IPSS）、최대뇨류솔（maximum flow rate，Qmax）비교무통계학차이（P ＞0.05）。량조간수술시간、전렬선절제중량、술후류치뇨관시간화주원시간、술중수혈솔비교，차이유통계학의의（P ＜0.05）。량조간뇨도협착、뇨실금급이차수술발생솔비교，차이무통계학의의（P ＞0.05）。결론LP 화 OP 대대체적전렬선 BPH 유상동적근기료효。LP 조수술시간장、절제전렬선조직소，단시술후방광충세시간、류치뇨관시간、주원시간단。
Objective To compare laparoscopic prostatectomy LP with Open prostatectomy OP for benign prostatic hy-perplasia with large volume. Methods The literature were identified systematically using Medline,Embase.Meta-analysis was performed by Review Manager 5.0. Results 3 CCTs were included.There was no significant difference between LP and OP in terms of IPSS,Qmax(P >0.05).LP was associated with less blood loss,a shorter irrigation,catheterization and hospital stay time except longer operating time.LP and OP were similar in terms of urethral stricture,incontinence,transfusion require-ment and rate of re-intervention. Conclusion LP served a significant improvement in IPSS,Qmax as well as OP.Although more operating time and less resected tissue,LP has several advantages over OP.It was as safe as OP in terms of adverse events.