化工进展
化工進展
화공진전
CHEMICAL INDUSTRY AND ENGINEERING PROGRESS
2014年
10期
2665-2675,2699
,共12页
两亲性聚合物%分子自组装%聚集作用%纳米粒子%形态学
兩親性聚閤物%分子自組裝%聚集作用%納米粒子%形態學
량친성취합물%분자자조장%취집작용%납미입자%형태학
amphiphilic polymers%molecular self-assembly%aggregation%nanoparticles%morphology
两亲性聚合物以其同时具有亲水和疏水链段的独特结构，在生物医药、纳米技术等领域有广泛的用途。本文主要介绍了两亲性聚合物通过分子自组装形成聚集体的研究进展，详细论述了几种分子自组装聚集体的制备，包括结构、组成、分子量控制的简单聚集体、半结晶聚集体、交联聚集体以及具有刺激响应性（pH值响应性、温度响应性、pH值/温度双重响应性、氧化还原响应性、溶剂极性响应性等）的智能型聚集体，两亲性聚合物结构的可控性以及如何提高聚集体的稳定性成为国内外专家研究的重点，指出结晶诱导分子自组装及智能型分子自组装是未来研究的热点。
兩親性聚閤物以其同時具有親水和疏水鏈段的獨特結構，在生物醫藥、納米技術等領域有廣汎的用途。本文主要介紹瞭兩親性聚閤物通過分子自組裝形成聚集體的研究進展，詳細論述瞭幾種分子自組裝聚集體的製備，包括結構、組成、分子量控製的簡單聚集體、半結晶聚集體、交聯聚集體以及具有刺激響應性（pH值響應性、溫度響應性、pH值/溫度雙重響應性、氧化還原響應性、溶劑極性響應性等）的智能型聚集體，兩親性聚閤物結構的可控性以及如何提高聚集體的穩定性成為國內外專傢研究的重點，指齣結晶誘導分子自組裝及智能型分子自組裝是未來研究的熱點。
량친성취합물이기동시구유친수화소수련단적독특결구，재생물의약、납미기술등영역유엄범적용도。본문주요개소료량친성취합물통과분자자조장형성취집체적연구진전，상세논술료궤충분자자조장취집체적제비，포괄결구、조성、분자량공제적간단취집체、반결정취집체、교련취집체이급구유자격향응성（pH치향응성、온도향응성、pH치/온도쌍중향응성、양화환원향응성、용제겁성향응성등）적지능형취집체，량친성취합물결구적가공성이급여하제고취집체적은정성성위국내외전가연구적중점，지출결정유도분자자조장급지능형분자자조장시미래연구적열점。
Amphiphilic polymers have a wide range of applications in biomedicine and nanotechnology because of their unique structures with both hydrophilic chains and hydrophobic chains. Research progress of aggregates formed by molecular self-assembly of amphiphilic polymers is introduced. Some molecular self-assembled aggregates,such as aggregates controlled by structure,composition and molecular weight,semi-crystalline aggregates,crosslinked aggregates,smart aggregates with stimuli-responsiveness (such as pH,temperature,pH/temperature,redox,solvent polarity) are discussed. Research efforts have been focused on controllability of amphiphilic polymers structure and enhancement of stability of aggregates. Crystallization induced molecular self-assembly and smart molecular self-assembly are future research trends.
