中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
16期
102-103
,共2页
复方汉防己%肝硬化%机理%疗效
複方漢防己%肝硬化%機理%療效
복방한방기%간경화%궤리%료효
Compound Hanfangji Granules%liver cirrhosis%mechanism%curative ffect
目的：观察复方汉防己颗粒治疗肝硬化的临床疗效并探讨其机理。方法选择确诊的肝硬化患者320例，随机分为观察组与对照组，各160例。对照组采用常规肝硬化治疗，观察组给予患者服用复方汉防己颗粒，疗程均为1个月。观察临床疗效，检测患者治疗前后白蛋白含量、总胆红素含量、门静脉内径、丙氨酸氨基转移酶含量。结果观察组患者治疗有效率为86.26%，明显高于对照组的59.38%（ P <0.05）。治疗后观察组白蛋白含量（32±5）g / L，明显高于对照组的（29±4）g / L；观察组总胆红素含量为（20.3±11.7）μmol / L，显著低于对照组的（23.2±10.5）μmol / L；观察组门静脉内径为（1.1±0.3）cm，明显短于对照组的（1.3±0.2）cm；观察组丙氨酸氨基转移酶含量为（0.83±0.23）μmol / L，显著低于对照组的（0.93±0.22）μmol / L（ P <0.05）。结论与常用的保肝治疗方法相比，复方汉防己颗粒治疗肝硬化具有较高的治疗有效率，症状改善明显，用药方式简单，价格适宜。
目的：觀察複方漢防己顆粒治療肝硬化的臨床療效併探討其機理。方法選擇確診的肝硬化患者320例，隨機分為觀察組與對照組，各160例。對照組採用常規肝硬化治療，觀察組給予患者服用複方漢防己顆粒，療程均為1箇月。觀察臨床療效，檢測患者治療前後白蛋白含量、總膽紅素含量、門靜脈內徑、丙氨痠氨基轉移酶含量。結果觀察組患者治療有效率為86.26%，明顯高于對照組的59.38%（ P <0.05）。治療後觀察組白蛋白含量（32±5）g / L，明顯高于對照組的（29±4）g / L；觀察組總膽紅素含量為（20.3±11.7）μmol / L，顯著低于對照組的（23.2±10.5）μmol / L；觀察組門靜脈內徑為（1.1±0.3）cm，明顯短于對照組的（1.3±0.2）cm；觀察組丙氨痠氨基轉移酶含量為（0.83±0.23）μmol / L，顯著低于對照組的（0.93±0.22）μmol / L（ P <0.05）。結論與常用的保肝治療方法相比，複方漢防己顆粒治療肝硬化具有較高的治療有效率，癥狀改善明顯，用藥方式簡單，價格適宜。
목적：관찰복방한방기과립치료간경화적림상료효병탐토기궤리。방법선택학진적간경화환자320례，수궤분위관찰조여대조조，각160례。대조조채용상규간경화치료，관찰조급여환자복용복방한방기과립，료정균위1개월。관찰림상료효，검측환자치료전후백단백함량、총담홍소함량、문정맥내경、병안산안기전이매함량。결과관찰조환자치료유효솔위86.26%，명현고우대조조적59.38%（ P <0.05）。치료후관찰조백단백함량（32±5）g / L，명현고우대조조적（29±4）g / L；관찰조총담홍소함량위（20.3±11.7）μmol / L，현저저우대조조적（23.2±10.5）μmol / L；관찰조문정맥내경위（1.1±0.3）cm，명현단우대조조적（1.3±0.2）cm；관찰조병안산안기전이매함량위（0.83±0.23）μmol / L，현저저우대조조적（0.93±0.22）μmol / L（ P <0.05）。결론여상용적보간치료방법상비，복방한방기과립치료간경화구유교고적치료유효솔，증상개선명현，용약방식간단，개격괄의。
Objective To observe the clinical effect of Compound Hanfangji Granules in the treatment of liver cirrhosis,and to explore its mechanism to provide the reference for clinic. Methods 320 cases of liver cirrhosis were selected and randomly divided into the observation group(160 cases)and the control group(160 cases). The control group was treated by the routine treatment of liver cir-rhosis,while the observation group was given Compound Hanfangji Granules. The treatment course in the two groups was 1 month. The clinical effects after treatment were observed. Albumin,total bilirubin,portal vein diameter,alanine aminotransferase were detected and the differences were compared between before and after treatment. Results The effective rate of the observation group was 86. 26% ,which was significantly higher than 59. 38% in the control group,the difference was statistically significant( P < 0. 05). The albumin content after treatment in the observation group was(32 ± 5)g / L,which was significantly higher than(29 ± 4 )g / L in the control group;the to-tal bilirubin content in the observation group was(20. 3 ± 11. 7)μmol / L,which was significantly lower than( 23. 2 ± 10. 5)μmol / L in the control group;the portal vein diameter in observation group was(1. 1 ± 0 3)cm,which was significantly shorter than(1. 3 ± 0. 2)cm in the control group;the GPT content in the observation group was(0. 83 ± 0. 23)μmol / L,which was significantly lower than(0. 93 ± 0. 22)μmol / L in the control group,the above differences were statistically significant( P < 0. 05). Conclusion Compared with usual liver - protective therapy,clinical use of Compound Hanfangji Granules has higher effective rate in the treatment of liver cirrhosis,obvi-ously improves the symptoms with simple administration mode and proper price.
