CAJ | 학술논문

综述了近年来鎓盐类多肽缩合剂在有机合成中应用的研究进展。鎓盐类多肽缩合剂主要分为两大类：磷正离子缩合剂和脲正离子缩合剂，由于其发展迅速，不仅改良了传统的鎓盐类缩合剂，扩展了鎓盐类多肽缩合剂的种类，而且出现了新型的盐类缩合剂，如亚胺正离子型缩合剂等。这类缩合剂不仅可以用于酯和酰胺的合成，而且可以用于合成小肽和生物活性肽，从而扩展到整个有机合成领域。
종술료근년래옹염류다태축합제재유궤합성중응용적연구진전。옹염류다태축합제주요분위량대류：린정리자축합제화뇨정리자축합제，유우기발전신속，불부개량료전통적옹염류축합제，확전료옹염류다태축합제적충류，이차출현료신형적염류축합제，여아알정리자형축합제등。저류축합제불부가이용우지화선알적합성，이차가이용우합성소태화생물활성태，종이확전도정개유궤합성영역。
The advances in research on the onium -type coupling reagents in organic synthesis were reviewed.The onium-type coupling reagents were mainly divided into two categories of phosphonium reagents and uronium reagents .With the rapid development of coupling reagents , there was not only the novel agent , but also emergence of new condensing agent such as new immonium reagents.Its application was from conventional synthetic of amide and ester to the synthesis of bioactive peptides and small peptides , which extended to the entire field of organic synthesis.