CAJ | 학술논문

药物化学知识体系的形成和发展与有机化学、生物化学、分子生物学等基础学科息息相关，综合性强，且存在药物种类繁多、药物理化性质复杂、构效关系与作用机制不易理解等问题。本文通过以药物结构为教学核心，构建药物化学知识网，旨在克服教学过程中上述问题，避免知识点罗列的灌输性教学，降低教学难度和学习难度，并引导学生进一步掌握药物的构效关系、药理作用，讲解新药研发的创新思路，培养学生设计新药的思维。
약물화학지식체계적형성화발전여유궤화학、생물화학、분자생물학등기출학과식식상관，종합성강，차존재약물충류번다、약물이화성질복잡、구효관계여작용궤제불역리해등문제。본문통과이약물결구위교학핵심，구건약물화학지식망，지재극복교학과정중상술문제，피면지식점라렬적관수성교학，강저교학난도화학습난도，병인도학생진일보장악약물적구효관계、약리작용，강해신약연발적창신사로，배양학생설계신약적사유。
The formation and development of the knowledge system of medicinal chemistry were closely related to organic chemistry , biochemistry and molecular chemistry.The complicate drug physical and chemical properties , the intricate structure -activity relationship and the complex mechanism of a variety of drugs contributed to the difficulty in learning this comprehensive course.A successful endeavor in drug -structure -centered teaching method was made to reduce the degree of difficulties of both teaching and learning.Furthermore , students were guided in mastering the structure-activity relationship and pharmacological effects of various drugs with the approach and their ideation in design new drugs were cultivated by interpreting the innovative ideas of drug research and development.