广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2014年
17期
122-123,151
,共3页
气相色谱%乌洛托品%甲醇残留
氣相色譜%烏洛託品%甲醇殘留
기상색보%오락탁품%갑순잔류
gas chromatography%methenamine%methanol residues
建立了毛细管气相色谱法，用于测定乌洛托品中残留的甲醇含量。采用HP-5毛细管色谱柱， FID检测器，在确定的色谱条件下，甲醇浓度在5.83～583μg/mL范围内，线性关系良好，加样回收率为96.70％～102.47％，最低检出限为0.24 ng。该方法的灵敏度和准确度均符合分析要求，而且方法可靠，可用于乌洛托品原料药中甲醇残留量的测定。
建立瞭毛細管氣相色譜法，用于測定烏洛託品中殘留的甲醇含量。採用HP-5毛細管色譜柱， FID檢測器，在確定的色譜條件下，甲醇濃度在5.83～583μg/mL範圍內，線性關繫良好，加樣迴收率為96.70％～102.47％，最低檢齣限為0.24 ng。該方法的靈敏度和準確度均符閤分析要求，而且方法可靠，可用于烏洛託品原料藥中甲醇殘留量的測定。
건립료모세관기상색보법，용우측정오락탁품중잔류적갑순함량。채용HP-5모세관색보주， FID검측기，재학정적색보조건하，갑순농도재5.83～583μg/mL범위내，선성관계량호，가양회수솔위96.70％～102.47％，최저검출한위0.24 ng。해방법적령민도화준학도균부합분석요구，이차방법가고，가용우오락탁품원료약중갑순잔류량적측정。
A gas chromatography method was established to determine the content of methanol in methenamine .The contents of methanol were quantitatively determined by capillary gas chromatography on HP -5 capillary column , with FID detector.The excellent linearity was obtained in 5.83~583 μg/mL under the definite chromatographic conditions.The recoveries of spiked samples were in the range of 96.70%~102.47%.The minimum detection limit was 0.24 ng.Both the sensitivity and accuracy fitted the bill.The positive means can be used for the quantitative analysis of the methanol in methenamine.
