CAJ | 학술논문

目的：探讨微生态制剂对绞窄性肠梗阻肠道菌群失调的治疗作用。方法：绞窄性肠梗阻208例，按入院先后(3：1)分为两组：治疗组(156例)为常规治疗+术中及术后用微生态制剂；对照组(52例)为常规治疗而不用微生态制剂。以腹腔内渗液内毒素、D-乳酸水平反映肠通道性变化。术中两组绞窄段、绞窄前段及后段肠内容物作细菌培养。结果：绞窄性肠梗阻患者存在明显的肠道菌群失调；微生态制剂治疗，可迅速使肠道主要优势菌群(双歧杆菌和乳酸杆菌)增殖，病原菌(大肠杆菌和肠球菌)被抑制；且肠通道性较早康复。结论：微生态制剂可尽快使绞窄性肠梗阻肠道菌群失调恢复正常，肠通道性较早康复。
목적：탐토미생태제제대교착성장경조장도균군실조적치료작용。방법：교착성장경조208례，안입원선후(3：1)분위량조：치료조(156례)위상규치료+술중급술후용미생태제제；대조조(52례)위상규치료이불용미생태제제。이복강내삼액내독소、D-유산수평반영장통도성변화。술중량조교착단、교착전단급후단장내용물작세균배양。결과：교착성장경조환자존재명현적장도균군실조；미생태제제치료，가신속사장도주요우세균군(쌍기간균화유산간균)증식，병원균(대장간균화장구균)피억제；차장통도성교조강복。결론：미생태제제가진쾌사교착성장경조장도균군실조회복정상，장통도성교조강복。
To evaluate the influence of microecological peparations on intestinal flora imbalance in diseases of strangulated intestinal obstruction.Methods:208 patients suffering from strangulated intestinal obstruction were divided into test group(n=156,treated by microecological preparations ) and control group(n=52).D-lactate,endotoxin in abdominal fluid were detected in all the patients.The effects of microecological preparations on intestinal flora imbalance were invested.Results:There is intestinal flora imbalance in diseases of strangulated intestinal obstruction.concentration of D-lactate and endotoxin in test group declined to normal range at 3d after operation,while in control group reduced to normal range at 5d after operation.At 3、5 days,the Bi fidobecterium and Lactobacillus in the test group were much higher than those of the control group;While the Enterobacterium and Enterococcus in the test group were much lower than those of the control group.The intestinal flora imbalance in test group recovered to normal range rapidly. Conclusion:Microecological preparetinons could have the rapid and definite correcting action on treating intestinal flora imbalance in diseases of strangulated intestinal obstruction.