CAJ | 학술논문

目的：探讨脑脑梗死患者静息心率的水平与超敏C反应蛋白(hs-CRP)及Essen卒中危险评分的关系。方法选择2013年3月~2014年3月南京市六合区中医院内科的脑梗死患者101例，其中初次或已经发生脑梗死患者再次经头颅CT和(或)MRI证实有新的梗死灶的急性期组58例，发生过脑梗死患者再次因头昏、肢体乏力及定期“保健”输液，经头颅CT和(或)MRI证实无新发脑梗死病灶的后遗症期组43例。进行血浆hs-CRP、静息心率水平和Essen卒中危险评分的测定，比较两组的静息心率水平与hs-CRP水平及Essen卒中危险评分的关系。结果①急性期组脑梗死患者静息心率与hs-CRP水平呈正相关(r=0.284，P<0.05)；静息心率水平与Essen评分无相关性(P>0.05)。②后遗症期组脑梗死患者的静息心率水平与hs-CRP及Essen评分均无相关性(P>0.05)。③两组患者年龄、性别、高血压患病率、糖尿病患病率、吸烟率、静息心率、hs-CRP、纤维蛋白原、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、体重指数比较，差异无统计学意义(P>0.05)；两组高密度脂蛋白胆固醇、Essen评分比较，差异有统计学意义(P<0.05)。结论脑梗死患者ESSEN卒中危险评分与hs-CRP水平均能反映患者的危险程度，但静息心率水平同急性期脑梗死患者Hs-CRP水平有良好相关性。
목적：탐토뇌뇌경사환자정식심솔적수평여초민C반응단백(hs-CRP)급Essen졸중위험평분적관계。방법선택2013년3월~2014년3월남경시륙합구중의원내과적뇌경사환자101례，기중초차혹이경발생뇌경사환자재차경두로CT화(혹)MRI증실유신적경사조적급성기조58례，발생과뇌경사환자재차인두혼、지체핍력급정기“보건”수액，경두로CT화(혹)MRI증실무신발뇌경사병조적후유증기조43례。진행혈장hs-CRP、정식심솔수평화Essen졸중위험평분적측정，비교량조적정식심솔수평여hs-CRP수평급Essen졸중위험평분적관계。결과①급성기조뇌경사환자정식심솔여hs-CRP수평정정상관(r=0.284，P<0.05)；정식심솔수평여Essen평분무상관성(P>0.05)。②후유증기조뇌경사환자적정식심솔수평여hs-CRP급Essen평분균무상관성(P>0.05)。③량조환자년령、성별、고혈압환병솔、당뇨병환병솔、흡연솔、정식심솔、hs-CRP、섬유단백원、총담고순、삼선감유、저밀도지단백담고순、체중지수비교，차이무통계학의의(P>0.05)；량조고밀도지단백담고순、Essen평분비교，차이유통계학의의(P<0.05)。결론뇌경사환자ESSEN졸중위험평분여hs-CRP수평균능반영환자적위험정도，단정식심솔수평동급성기뇌경사환자Hs-CRP수평유량호상관성。
Objective To investigate the relationship among the level of resting heart rate, high-sensitivity C-reactive protein and Essen stroke risk score among patients with cerebral infarction. Methods 101 patients with cerebral infarc-tion admitted by Chinese Medicine Hospital of Liuhe District of Nanjing City from March 2013 to March 2014 were se-lected. 58 patients with cerebral infarction under acute condition for the first time and had developed new infarction le-sions confirmed by CT and (or) MRI were as the acute phase group; 43 patients who have had cerebral infarction were confirmed by brain CT and (or) MRI that no new cerebral lesion had occurred after sequelas like cerebral infarction dizziness and limb weakness or periodic "health" infusion were as the sequelae stage group. The high-sensitivity C-re-active protein, resting heart rate and Essen stroke risk score of two groups were detected, and the resting heart rate, the level of high-sensitivity C-reactive protein and Essen stroke risk score between the two groups were compared. Results①Among patients with acute cerebral infarction, the resting heart rate and high-sensitivity C-reactive protein levels are positively correlated (r =0.284, P< 0.05); the resting heart rate levels and Essen score showed no correlation (P>0.05).②Among patients with cerebral infarction sequelas, the resting heart rate levels, high-sensitivity C-reactive pro-tein and Essen scoreed show no correlation (P>0.05).③The age, gender, prevalence of hypertension, diabetes preva-lence, smoking rates, resting heart rate, high-sensitivity C-reactive protein, fibrinogen, total cholesterol, triglyceride, low density lipoprotein cholesterol or body mass index were not statistically significant among the two groups (P >0.05);yet the high-density lipoprotein cholesterol and Essen scores were statistically significant (P<0.05). Conclu-sion The degree of risk among patients with cerebral infarction can be seen from Essen stroke risk score and hs-CRP levels, but the resting heart rate and Hs-CRP levels have a good correlation in patients with acute cerebral infarction.