CAJ | 학술논문

目的：运用药物经济学的分析方法，探讨儿童蜂窝织炎的最佳药物治疗方案，以最低成本获得最佳的治疗效果。方法采用药物经济学方法分析河北省儿童医院2012年1月~2014年3月儿童诊断为蜂窝织炎的155份病历，根据给药方案分成5组，进行成本-效果分析。结果头孢硫脒、头孢硫脒+甲硝唑、头孢替唑钠、头孢曲松钠及头孢孟多酯钠的有效率分别为97.14%、98.33%、95.65%、95.45%和93.33%，治疗效果比较，差异无统计学意义(χ2=1.863，P=0.761)，各组治疗成本分别为3362.08、3551.05、4549.11、3916.75、4053.82元，各组C/E值分别为34.61、36.11、47.56、41.03、43.44，其中头孢硫脒所用治疗方案成本最小，成本-效果比值最低。结论头孢硫脒给药方案是治疗儿童蜂窝织炎的最佳方案。
목적：운용약물경제학적분석방법，탐토인동봉와직염적최가약물치료방안，이최저성본획득최가적치료효과。방법채용약물경제학방법분석하북성인동의원2012년1월~2014년3월인동진단위봉와직염적155빈병력，근거급약방안분성5조，진행성본-효과분석。결과두포류미、두포류미+갑초서、두포체서납、두포곡송납급두포맹다지납적유효솔분별위97.14%、98.33%、95.65%、95.45%화93.33%，치료효과비교，차이무통계학의의(χ2=1.863，P=0.761)，각조치료성본분별위3362.08、3551.05、4549.11、3916.75、4053.82원，각조C/E치분별위34.61、36.11、47.56、41.03、43.44，기중두포류미소용치료방안성본최소，성본-효과비치최저。결론두포류미급약방안시치료인동봉와직염적최가방안。
Objective To obtain the optimal treatment with the lowest cost and the best effect on children with celluli-tis by pharmacoeconomics. Methods 155 cases of children with cellulitis from January 2012 to March 2014 in the Children’s Hospital of Hebei Province were analyzed, the cost-effectiveness of these 5 treatment groups which were di-vided according to dosage regimen was compared by pharmacoeconomics. Results The effective rates of Cefathiamidine, Cefathiamidine and Metronidazole, Ceftezole Sodium, Ceftriaxone Sodium, Cefamandole Sodium were 97.14%, 98.33%, 95.65%, 95.45%and 93.33% respectively. There was no significant difference in treatment effect of 5 treatment groups (χ2=1.863, P= 0.761). The treatment costs of each groups were 3362.08, 3551.05, 4549.11, 3916.75, 4053.82 yuan re-spectively, and C/E were 34.61, 36.11, 47.56, 41.03, 43.44 respectively. The treatment cost of Cefathiamidine was the smallest, so was the cost-effectiveness. Conclusion Cefathiamidine is the best treatment for children with cellulitis.