CAJ | 학술논문

目的：探讨缺血性脑血管病患者血浆溶血磷脂酸极性相似总磷脂(AP)及椎动脉峰时的情况。方法收集2012年10月~2013年2月在石家庄市第八医院内科住院的缺血性脑血管病患者220例(缺血性脑血管病组)，分为脑梗死组(110例)与短暂性脑缺血发作(TIA)组(110例)，并选取同时期在门诊进行体检100名健康体检者作为对照组。采用比色法检测AP，彩色多普勒超声显像仪作椎动脉峰时测定。结果缺血性脑血管病组、脑梗死组和TIA组的AP的检测阳性率(93.6%、96.3%、90.9%)及椎动脉峰时延长的阳性率(94.5%、90.9%、98.1%)显著高于对照组(55.0%、35.0%)，差异有高度统计学意义(P<0.01)，而脑梗死组和TIA组两组间AP的阳性率及椎动脉峰时阳性比较，差异无统计学意义(P>0.05)；缺血性脑病组的AP、椎动脉峰时检测分别为(6.54±1.88)U、(0.163±0.013)s,与对照组[(5.82±1.03)U、(0.148±0.016)s]比较，差异有统计学意义(P<0.05)。结论缺血性脑血管病与AP及椎动脉峰时有关。
목적：탐토결혈성뇌혈관병환자혈장용혈린지산겁성상사총린지(AP)급추동맥봉시적정황。방법수집2012년10월~2013년2월재석가장시제팔의원내과주원적결혈성뇌혈관병환자220례(결혈성뇌혈관병조)，분위뇌경사조(110례)여단잠성뇌결혈발작(TIA)조(110례)，병선취동시기재문진진행체검100명건강체검자작위대조조。채용비색법검측AP，채색다보륵초성현상의작추동맥봉시측정。결과결혈성뇌혈관병조、뇌경사조화TIA조적AP적검측양성솔(93.6%、96.3%、90.9%)급추동맥봉시연장적양성솔(94.5%、90.9%、98.1%)현저고우대조조(55.0%、35.0%)，차이유고도통계학의의(P<0.01)，이뇌경사조화TIA조량조간AP적양성솔급추동맥봉시양성비교，차이무통계학의의(P>0.05)；결혈성뇌병조적AP、추동맥봉시검측분별위(6.54±1.88)U、(0.163±0.013)s,여대조조[(5.82±1.03)U、(0.148±0.016)s]비교，차이유통계학의의(P<0.05)。결론결혈성뇌혈관병여AP급추동맥봉시유관。
Objective To explore the situation of plasma lysophosphatidic acid of total phospholipids (AP) and verte-bral artery peak in patients with ischemic cerebrovascular disease. Methods From October 2012 to February 2013, at department of Internal Medicine in the Eighth Hospital of Shijiazhuang City,220 patients with ischemic cerebrovascular disease patients hospitalized were selected (ischemic cerebrovascular disease group), divided into cerebral infarction group (110 cases) and transient ischemic attack (TIA) group (110 cases), at the same period, 100 cases health examina-tion people in the outpatient were selected as control group. The colorimetry was used to detect AP, vertebral artery peak was determined by color Doppler ultrasonic imaging instrument. Results The positive rate of AP (93.6%, 96.3%, 90.9%) and vertebral artery peak extension (94.5%, 90.9%, 98.1%) in ischemic cerebrovascular disease group, infarction group and TIA group were higher than those in control group (55.0%, 35.0%), the differences were statistically significant (P<0.01), but those in infarction group and TIA group were compared, the differences were not statistically significant (P>0.05). AP and vertebral artery peak in ischemic cerebrovascular disease group were (6.54±1.88) U and (0.163±0.013) s, compared with control group [(5.82±1.03) U, (0.148±0.016) s], the differences were statistically significant (P < 0.05). Conclusion Ischemic cerebrovascular disease is associated with AP and vertebral artery peak.