中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
28期
26-28
,共3页
小儿肺炎%微量元素%免疫球蛋白%易感因素
小兒肺炎%微量元素%免疫毬蛋白%易感因素
소인폐염%미량원소%면역구단백%역감인소
Infantile pneumonia%Microelement%Immune globulin%Predisposing factors
目的：探讨小儿肺炎患儿的微量元素、免疫球蛋白与易感因素。方法收治呼吸道反复感染患儿(观察组)及门诊体检的健康儿童(对照组)各80例,采用自制的小儿肺炎易感因素调查表,记录两组儿童血常规、血金属元素及血免疫球蛋白等检查结果。采用χ2检验和t检验进行易感因素的单因素分析,采用非条件Logistic回归模型进行易感因素的多因素分析。结果观察组的血钙、铁元素、血IgA和IgG明显低于对照组,差异具有统计学意义(P<0.05)。将与小儿肺炎相关的因素引入多因素Logistic回归分析,结果显示：胎次≥3次(OR=2.988,95%CI 1.249~5.147)、被动吸烟(OR=6.812,95%CI 2.143~13.764)、低钙血症(OR=3.304,95%CI 1.203~6.056)、血清IgA<230 mg/L(OR=5.237,95%CI 1.103~10.721)和IgG<5 g/L(OR=5.408,95%CI 1.282~11.302)、抗生素与激素的使用(OR=8.542,95%CI 3.762~16.997)、生活环境(幼儿园)(OR=3.251,95%CI 1.377~6.223)为小儿肺炎的独立易感因素。结论小儿肺炎与多种因素有关,应针对易感因素做好预防工作。
目的：探討小兒肺炎患兒的微量元素、免疫毬蛋白與易感因素。方法收治呼吸道反複感染患兒(觀察組)及門診體檢的健康兒童(對照組)各80例,採用自製的小兒肺炎易感因素調查錶,記錄兩組兒童血常規、血金屬元素及血免疫毬蛋白等檢查結果。採用χ2檢驗和t檢驗進行易感因素的單因素分析,採用非條件Logistic迴歸模型進行易感因素的多因素分析。結果觀察組的血鈣、鐵元素、血IgA和IgG明顯低于對照組,差異具有統計學意義(P<0.05)。將與小兒肺炎相關的因素引入多因素Logistic迴歸分析,結果顯示：胎次≥3次(OR=2.988,95%CI 1.249~5.147)、被動吸煙(OR=6.812,95%CI 2.143~13.764)、低鈣血癥(OR=3.304,95%CI 1.203~6.056)、血清IgA<230 mg/L(OR=5.237,95%CI 1.103~10.721)和IgG<5 g/L(OR=5.408,95%CI 1.282~11.302)、抗生素與激素的使用(OR=8.542,95%CI 3.762~16.997)、生活環境(幼兒園)(OR=3.251,95%CI 1.377~6.223)為小兒肺炎的獨立易感因素。結論小兒肺炎與多種因素有關,應針對易感因素做好預防工作。
목적：탐토소인폐염환인적미량원소、면역구단백여역감인소。방법수치호흡도반복감염환인(관찰조)급문진체검적건강인동(대조조)각80례,채용자제적소인폐염역감인소조사표,기록량조인동혈상규、혈금속원소급혈면역구단백등검사결과。채용χ2검험화t검험진행역감인소적단인소분석,채용비조건Logistic회귀모형진행역감인소적다인소분석。결과관찰조적혈개、철원소、혈IgA화IgG명현저우대조조,차이구유통계학의의(P<0.05)。장여소인폐염상관적인소인입다인소Logistic회귀분석,결과현시：태차≥3차(OR=2.988,95%CI 1.249~5.147)、피동흡연(OR=6.812,95%CI 2.143~13.764)、저개혈증(OR=3.304,95%CI 1.203~6.056)、혈청IgA<230 mg/L(OR=5.237,95%CI 1.103~10.721)화IgG<5 g/L(OR=5.408,95%CI 1.282~11.302)、항생소여격소적사용(OR=8.542,95%CI 3.762~16.997)、생활배경(유인완)(OR=3.251,95%CI 1.377~6.223)위소인폐염적독립역감인소。결론소인폐염여다충인소유관,응침대역감인소주호예방공작。
Objective To explore microelement and immune globulin and predisposing factors of infantile pneumonia. Methods Children with repeated respiratory infection in our hospital (observation group) and outpatient healthy children (control group) were selected as 80 cases in each group. The blood routine, blood metallic elements, and blood immune globulin of the two groups were recorded using self-designed susceptibility factors questionnaire. The analysis single factor of predisposing factors was made byχ2 test and t test. The multifactors of predisposing factors were analyzed by unconditioned Logistic regression model. Results Blood calcium, iron, IgA and IgG of the observation group were obviously lower than those of the control group, and the difference had statistical significance (P<0.05). The infantile pneumonia related factors analyzed by multi-factor Logistic regression analysis showed the independent predisposing factors of infantile pneumonia were≥3 times (OR=2.988, 95%CI 1.249~5.147), passive smoking (OR=6.812, 95%CI 2.143~13.764), hypocalcemia (OR=3.304, 95%CI 1.203~6.056), serum IgA<230 mg/L (OR=5.237, 95%CI 1.103~10.721), IgG<5 g/L (OR=5.408, 95%CI 1.282~11.302), the use of antibiotics and hormones (OR=8.542, 95%CI 3.762~16.997), and living environment (kindergarten) (OR=3.251, 95%CI 1.377~6.223). Conclusion A variety of factors are related to infantile pneumonia, and the prevention work should be made according to predisposing factors.
