岭南急诊医学杂志
嶺南急診醫學雜誌
령남급진의학잡지
LINGNAN JOURNAL OF EMERGENCY MEDICINE
2014年
3期
214-216
,共3页
利巴韦林%炎琥宁%轮状病毒肠炎%临床效果
利巴韋林%炎琥寧%輪狀病毒腸炎%臨床效果
리파위림%염호저%륜상병독장염%림상효과
Ribavirin%Yanhuning%Rotavirus enteritis%clinical effect
目的：观察利巴韦林、炎琥宁治疗婴幼儿轮状病毒肠炎的临床疗效。方法：将我院诊疗的婴幼儿轮状病毒肠炎患者236例随机分为利巴韦林组（A组）、炎琥宁组（B 组）、对照组（C 组），再按入院时距发病时间分为病程0-48 h 组，病程＞48 h 组。 C 组仅给予补液、维持水电解质平衡等基础治疗；A 组加用利巴韦林（10-15） mg/（kg·d）静脉滴注，B 组加用炎琥宁（5-8）mg/（kg·d）静脉滴注，比较各组患儿发热持续时间、退热时间、腹泻性状及次数恢复正常时总病程时间。结果：在病程0-48 h 组中，A 组、B 组的退热时间均明显短于 C 组，B 组总病程明显短于C 组，P 均＜0．05；在病程＞48 h 组中，A组、B 组、C 组退热时间均无明显差异，B 组总病程短于A组、C 组。结论：在起病0-48 h 间使用利巴韦林、炎琥宁有助于轮状病毒肠炎患者退热，使用炎琥宁可缩短病程，有助于改善腹泻症状。
目的：觀察利巴韋林、炎琥寧治療嬰幼兒輪狀病毒腸炎的臨床療效。方法：將我院診療的嬰幼兒輪狀病毒腸炎患者236例隨機分為利巴韋林組（A組）、炎琥寧組（B 組）、對照組（C 組），再按入院時距髮病時間分為病程0-48 h 組，病程＞48 h 組。 C 組僅給予補液、維持水電解質平衡等基礎治療；A 組加用利巴韋林（10-15） mg/（kg·d）靜脈滴註，B 組加用炎琥寧（5-8）mg/（kg·d）靜脈滴註，比較各組患兒髮熱持續時間、退熱時間、腹瀉性狀及次數恢複正常時總病程時間。結果：在病程0-48 h 組中，A 組、B 組的退熱時間均明顯短于 C 組，B 組總病程明顯短于C 組，P 均＜0．05；在病程＞48 h 組中，A組、B 組、C 組退熱時間均無明顯差異，B 組總病程短于A組、C 組。結論：在起病0-48 h 間使用利巴韋林、炎琥寧有助于輪狀病毒腸炎患者退熱，使用炎琥寧可縮短病程，有助于改善腹瀉癥狀。
목적：관찰리파위림、염호저치료영유인륜상병독장염적림상료효。방법：장아원진료적영유인륜상병독장염환자236례수궤분위리파위림조（A조）、염호저조（B 조）、대조조（C 조），재안입원시거발병시간분위병정0-48 h 조，병정＞48 h 조。 C 조부급여보액、유지수전해질평형등기출치료；A 조가용리파위림（10-15） mg/（kg·d）정맥적주，B 조가용염호저（5-8）mg/（kg·d）정맥적주，비교각조환인발열지속시간、퇴열시간、복사성상급차수회복정상시총병정시간。결과：재병정0-48 h 조중，A 조、B 조적퇴열시간균명현단우 C 조，B 조총병정명현단우C 조，P 균＜0．05；재병정＞48 h 조중，A조、B 조、C 조퇴열시간균무명현차이，B 조총병정단우A조、C 조。결론：재기병0-48 h 간사용리파위림、염호저유조우륜상병독장염환자퇴열，사용염호저가축단병정，유조우개선복사증상。
To observe the clinical effect of Ribavirin and Yanhuning for patients with infantile rotavirus enteritis. Method: 236 patients with infantile rotavirus enteritis were randomly divided into Ribavirin group (group A)、Yanhuning group(group B)and control group (group C). Among the three groups,there were divided into 0-48 h group and > 48 h group according the onset time to in-hospital. Based on the group C granted rehydration , maintain water and electrolyte balance, group A was given Ribavirin (10-15) mg/ (kg·d), intravenous drip, group B was given Yanhuning (5-8) mg/(kg.d), intravenous drip. The fever duration, fever to normal time, number of traits and diarrhea, the overall course were compared among the three groups. Results: At the 0-48 h groups, antifebrile time in both the group A and group B were significantly shorter than that in the group C , overall duration in group B was significantly shorter than that in the group C, all P<0.05. At the>48 h groups, antifebrile time in the three groups were no significant difference, but overall duration in group B was shorter than that in the other two groups. Conclusion: Using Ribavirin and Yanhuning can help antifebrile for patients with infantile rotavirus enteritis during the onset 0-48 hours , and Yanhuning may short the overall duration and help to improve symptoms of diarrhea for the cases.
