CAJ | 학술논문

目的：探讨强化调脂对老年急性心肌梗死（AMI）患者远期预后的影响。方法：将我院老年 AMI患者100例随机分为观察组和对照组，对照组给予常规剂量的调脂治疗，观察组给予强化调脂治疗，评估两组临床治疗效果及安全性。结果：治疗后观察组患者TC、TG、LDL-C、Hs-CRP 及 NT-proBNP 明显优于对照组，两组比较差异具有统计学意义（P ＜0．05）。治疗后观察组患者LVEF、IVST、LVPWT、LVEDD明显优于对照组，两组比较差异具有统计学意义（P ＜0．05）。治疗后随访2年，观察组患者主要不良心血管事件的发生率明显低于对照组，两组比较差异具有统计学意义（P ＜0．05）。结论：强化调脂治疗对老年急性心肌梗死远期疗效显著，值得应用。
목적：탐토강화조지대노년급성심기경사（AMI）환자원기예후적영향。방법：장아원노년 AMI환자100례수궤분위관찰조화대조조，대조조급여상규제량적조지치료，관찰조급여강화조지치료，평고량조림상치료효과급안전성。결과：치료후관찰조환자TC、TG、LDL-C、Hs-CRP 급 NT-proBNP 명현우우대조조，량조비교차이구유통계학의의（P ＜0．05）。치료후관찰조환자LVEF、IVST、LVPWT、LVEDD명현우우대조조，량조비교차이구유통계학의의（P ＜0．05）。치료후수방2년，관찰조환자주요불양심혈관사건적발생솔명현저우대조조，량조비교차이구유통계학의의（P ＜0．05）。결론：강화조지치료대노년급성심기경사원기료효현저，치득응용。
To evaluate the prostecdtive efficacy on effect of intensive cholesterol lowering therapy in the elderly with acute myocardial infarction. Method: The 100 patients with acute myocardial infarction were divided into the observe group and the control group. The control group received the cholesterol lowering treatment, and the observe group received the treatment of intensive cholesterol lowering. Results: The level of TC, TG, LDL-C, Hs-CRP and NT-proBNP in the observe group after treatment was superior to those in control group (P<0.05). The level of EF, IVST, LVPWT and LAEDD in the observe group after treatment was superior to those in control group (P<0.05). By following-up in 2 years, the MACES rate in the observe group after treatment was fewer than that in control group (P<0.05). Conclusions: The aggressive intensive cholesterol lowering therapy is effective to improve the prognosis of elderly AMI patients, so they are worth being used.