CAJ | 학술논문

稻瘟病是水稻生产上危害最严重的病害之一,针对该病的抗性基因在水稻中大多编码NBS-LRR类抗病蛋白质,该类蛋白质能够识别病原菌关联分子模式(Pathogen associated molecular pattern,PAMP),参与调控效应蛋白质激活免疫反应( Effector-triggered immunity,ETI)。 NBS-LRR类蛋白质结构多样、功能复杂,它们在植物抗病过程中扮演了重要的角色。本文主要对NBS-LRR类蛋白质的结构与功能、NBS-LRR类抗稻瘟病基因的克隆进展、NBS-LRR类蛋白质介导的信号传递途径以及目前研究中存在的问题进行了介绍。
도온병시수도생산상위해최엄중적병해지일,침대해병적항성기인재수도중대다편마NBS-LRR류항병단백질,해류단백질능구식별병원균관련분자모식(Pathogen associated molecular pattern,PAMP),삼여조공효응단백질격활면역반응( Effector-triggered immunity,ETI)。 NBS-LRR류단백질결구다양、공능복잡,타문재식물항병과정중분연료중요적각색。본문주요대NBS-LRR류단백질적결구여공능、NBS-LRR류항도온병기인적극륭진전、NBS-LRR류단백질개도적신호전체도경이급목전연구중존재적문제진행료개소。
Rice blast is one of the most important disease threatening the production of rice. In most cases, the ge-netic code of the disease resistance genes encodes NBS-LRR protein, which is capable of identifying PAMP ( pathogen asso-ciated molecular pattern) and being involved in controlling the pathogen effector that induces the ETI ( Effector-triggered immunity) . As NBS-LRR protein is diverse in structure and complex in functioning, they are playing a pivotal role in the process of plant disease resistance. In this review, the existing problems of structuring and functioning of NBS-LRR pro-tein, the progress of gene cloning of NBS-LRR and the signal mechanism of NBS-LRR protein-mediated transduction path-ways were introduced.