CAJ | 학술논문

观察右美托咪定对全麻腹腔镜手术术后CO2蓄积患者复苏阶段的影响。方法择期全麻行腹腔镜手术的患者，术毕前约40min测动脉血气，选取其中PaCO270~90mmHg ，pH<7.30的患者40例，随机分为对照组（N组）和右美托咪定组（D组）各20例。在手术结束前约30 min，N组患者给予0.9%氯化钠10mL静脉缓注，D组患者用右美托咪定配成4μg/mL浓度以0.8μg/kg剂量缓慢静注。记录两组患者在拔管时（T0）、拔管后5min（T1）、拔管后30min（T2）的心率、血压及Riker评分。两组患者从拔管开始到恢复满意可以送回病房所需时间（T3）。结果 D组患者在T0、T1、T2时的心率、血压及Riker评分与N组患者比较差异均有统计学意义（P<0.05）。两组患者从拔管开始到恢复满意可以送回病房所需时间的比较差异无统计学意义（P>0.05）。结论腹腔镜手术中，在CO2蓄积致高碳酸血症患者的麻醉复苏阶段，右美托咪定的作用是安全有效的。
관찰우미탁미정대전마복강경수술술후CO2축적환자복소계단적영향。방법택기전마행복강경수술적환자，술필전약40min측동맥혈기，선취기중PaCO270~90mmHg ，pH<7.30적환자40례，수궤분위대조조（N조）화우미탁미정조（D조）각20례。재수술결속전약30 min，N조환자급여0.9%록화납10mL정맥완주，D조환자용우미탁미정배성4μg/mL농도이0.8μg/kg제량완만정주。기록량조환자재발관시（T0）、발관후5min（T1）、발관후30min（T2）적심솔、혈압급Riker평분。량조환자종발관개시도회복만의가이송회병방소수시간（T3）。결과 D조환자재T0、T1、T2시적심솔、혈압급Riker평분여N조환자비교차이균유통계학의의（P<0.05）。량조환자종발관개시도회복만의가이송회병방소수시간적비교차이무통계학의의（P>0.05）。결론복강경수술중，재CO2축적치고탄산혈증환자적마취복소계단，우미탁미정적작용시안전유효적。
Objective To observe the effects of dexmedetomidine to anesthesia laparoscopic sur?gery on postoperative recovery phase CO2 accumulation in patients. Methods Chose patients un?dergoing laparoscopic operation. Before the end of operation about 40 min measured arterial blood gas. Selecting 40 cases of patients with PaCO2 70-90mmHg and pH<7. 30. They were randomly divid?ed into a control group(group N)and dexmedetomidine group(group D) with 20 cases in each. Be?fore the end of operation about 30 min. N group were treated with 0. 9%sodium chloride 10 mL slow intravenous injection. D group were given the dexmedetomidine dubbed 4 μg/mL slow intravenous with dose concentration 0.8 μg/kg. Recorded two groups of patients at extubation(T0),5 min after extubation(T1),30 min after extubation(T2)of heart rate,blood pressure and Riker score. Two groups of patients from extubation to can returned to the ward satisfaction time (T3). Results Compared the group D with N,at T0,T1,T2 time,heart rate,blood pressure,and Riker scores were statistically significant(P <0. 05). Comparison of the two groups was not statistically signifi?cant from extubation begin to restore satisfactory and could return to ward(P> 0. 05). Conclu?sion Laparoscopic surgery,CO2 accumulation in patients with hypercapnia recovery phase of anes?thesia,given dexmedetomidine is safe and effective.