CAJ | 학술논문

目的：探讨婴幼儿轮状病毒感染继发乳糖不耐受的分级治疗疗效。方法：收集并选择本院儿科113例轮状病毒感染继发乳糖不耐受的婴幼儿资料，按病情分级，重度病情分为实验组31例和对照组27例；轻度病情分为实验组26例和对照组29例。对照组实施常规治疗方案即抗感染、补充水电解质、服用胃肠黏膜保护剂和微生态制剂；实验组在常规治疗方案基础上加乳糖酶治疗。观察各组疗效。结果：重度病情实验组治疗有效率93．55％、对照组治疗有效率51．85％，两组差异有显著统计学意义（P＜0．01）；轻度病情实验组治疗有效率88．46％、对照组治疗有效率86．21％，两组差异无显著性意义（P＞0．05）。结论：婴幼儿轮状病毒感染性腹泻继发乳糖不耐受的治疗要区分病情轻重，对重度腹泻患儿应用乳糖酶治疗疗效显著，而轻度腹泻患儿常规治疗亦有疗效并且经济方便。
목적：탐토영유인륜상병독감염계발유당불내수적분급치료료효。방법：수집병선택본원인과113례륜상병독감염계발유당불내수적영유인자료，안병정분급，중도병정분위실험조31례화대조조27례；경도병정분위실험조26례화대조조29례。대조조실시상규치료방안즉항감염、보충수전해질、복용위장점막보호제화미생태제제；실험조재상규치료방안기출상가유당매치료。관찰각조료효。결과：중도병정실험조치료유효솔93．55％、대조조치료유효솔51．85％，량조차이유현저통계학의의（P＜0．01）；경도병정실험조치료유효솔88．46％、대조조치료유효솔86．21％，량조차이무현저성의의（P＞0．05）。결론：영유인륜상병독감염성복사계발유당불내수적치료요구분병정경중，대중도복사환인응용유당매치료료효현저，이경도복사환인상규치료역유료효병차경제방편。
Objective:To evaluate the staged therapeutic efficacies for management of infantile lactose intolerance secondary to the rotavirus infection . Methods:The clinical data were collected in 113 infants with lactose intolerance secondary to rotavirus infection admitted to our hospital ,and the infants were divided into different groups according to the disease severity,i.e.,severe disease(experimental group,n=31) and controls(control group,n=27);mild disease(experimental group,n=26) and controls(control group,n=29).The control group received conventional treatment by anti-infection,supple-ment of fluid and electrolyte ,oral gastrointestinal mucosal protective agent and microbial ecological agent ,whereas the experimental group were treated with additional lactase on the conventional protocol basis,and two groups were observed and compared regarding the therapeutic efficacies.Results:The effective rate was 93.55% for the experimental group of severe disease and 51.85% for the control counterparts,and the difference was significant (P<0.01), whereas 88.46% in the experimental group with mild disease and 86.21% in the corresponding controls responded well to the therapy,which showed no significant difference within groups(P>0.05).Conclusion:Treatment of the infantile lactose intolerance secondary to the rotavirus infection shall be in diverse plan.Supplement of lactose can be effective to infants with severe diarrhea ,yet conventional therapy may be effective and economical for those with mild disease.