实用肝脏病杂志
實用肝髒病雜誌
실용간장병잡지
JOURNAL OF CLINICAL HEPATOLOGY
2014年
4期
437-440
,共4页
郭恩爽(综述)%周福元(审校)
郭恩爽(綜述)%週福元(審校)
곽은상(종술)%주복원(심교)
肝细胞癌%乙型肝炎病毒%发生机制
肝細胞癌%乙型肝炎病毒%髮生機製
간세포암%을형간염병독%발생궤제
Hepatocellular carcinoma%Hepatitis B virus%Mechanisms
肝细胞癌（HCC）的发生与乙型肝炎病毒（HBV）感染密切相关。HBV感染所致的炎症反应、HBV X基因及其产物X蛋白、核心启动子突变、前S2区突变、剪接特异性蛋白等均可能参与HCC的发生发展。
肝細胞癌（HCC）的髮生與乙型肝炎病毒（HBV）感染密切相關。HBV感染所緻的炎癥反應、HBV X基因及其產物X蛋白、覈心啟動子突變、前S2區突變、剪接特異性蛋白等均可能參與HCC的髮生髮展。
간세포암（HCC）적발생여을형간염병독（HBV）감염밀절상관。HBV감염소치적염증반응、HBV X기인급기산물X단백、핵심계동자돌변、전S2구돌변、전접특이성단백등균가능삼여HCC적발생발전。
The infection of hepatitis B virus (HBV) plays an important role in the occurrence of hepatocellular carcinoma (HCC). Multiple factors may be involved in the hepatocarcinogenesis of HBV-related HCC,such as inflammatory response,HBV X gene and its protein,the mutation of HBV core promoter and pre-S 2 genes,HBV spliced protein and so on. We will discuss some progresses in this field.
