中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
14期
22-23
,共2页
血液透析%促红细胞生成素抵抗%尿毒清
血液透析%促紅細胞生成素牴抗%尿毒清
혈액투석%촉홍세포생성소저항%뇨독청
Hemodialysis%Erythropoietin resistance%Niaodu Qing
目的：探讨尿毒清对维持血透患者促红素抵抗的影响。方法：选取出现促红细胞生成素抵抗现象的24例患者，随机分成两组。两组患者均予常规的肾性贫血治疗，但治疗组中12例患者在此基础上加用尿毒清颗粒，疗程3个月。治疗前后观察Hb、Hct、hs-CRP、TNF-α、ERI的变化。结果：治疗组治疗后CRP、TNF-α、ERI较治疗前下降，Hb、Hct明显升高，与对照组相比，差异有统计学意义（P<0.05）。结论：中医药尿毒清不但可以改善透析患者的微炎症状态，而且对改善促红素抵抗具有良好的疗效。
目的：探討尿毒清對維持血透患者促紅素牴抗的影響。方法：選取齣現促紅細胞生成素牴抗現象的24例患者，隨機分成兩組。兩組患者均予常規的腎性貧血治療，但治療組中12例患者在此基礎上加用尿毒清顆粒，療程3箇月。治療前後觀察Hb、Hct、hs-CRP、TNF-α、ERI的變化。結果：治療組治療後CRP、TNF-α、ERI較治療前下降，Hb、Hct明顯升高，與對照組相比，差異有統計學意義（P<0.05）。結論：中醫藥尿毒清不但可以改善透析患者的微炎癥狀態，而且對改善促紅素牴抗具有良好的療效。
목적：탐토뇨독청대유지혈투환자촉홍소저항적영향。방법：선취출현촉홍세포생성소저항현상적24례환자，수궤분성량조。량조환자균여상규적신성빈혈치료，단치료조중12례환자재차기출상가용뇨독청과립，료정3개월。치료전후관찰Hb、Hct、hs-CRP、TNF-α、ERI적변화。결과：치료조치료후CRP、TNF-α、ERI교치료전하강，Hb、Hct명현승고，여대조조상비，차이유통계학의의（P<0.05）。결론：중의약뇨독청불단가이개선투석환자적미염증상태，이차대개선촉홍소저항구유량호적료효。
Objective: To observe effects of Niaodu Qing on erythropoietin resistance in maintenance hemodialysis (MHD) patients. Methods: 24 MHD patients with erythropoietin resistance were divided into two groups randomly. Therapy group was provided Niaodu Qing for 3 months, and the control group did not, all patients were provided routine treatment of renal anemia. Observe the changes in Hb, Hct, hs-CRP, TNF-α, ERI before and after treatment. Results: Therapy group CRP, TNF-α, ERI decreased than before treatment, Hb, Hct increased significantly, and the difference was statistically significant (P<0.05). Conclusion: Niaodu Qing can not only decrease the microinflammatory state of MHD patients, but also well improve erythropoietin resistance.
