中国卫生产业
中國衛生產業
중국위생산업
CHINA HEALTH INDUSTRY
2014年
18期
7-8
,共2页
米非司酮%绒毛%CD4+%CD8+
米非司酮%絨毛%CD4+%CD8+
미비사동%융모%CD4+%CD8+
Mifepristone%Villi%CD4+、CD8+
目的:探讨米非司酮对早孕绒毛CD4+、CD8+及细胞因子的影响。方法将本院2012年5月-2013年12月本院收治的100例早孕流产患者分为观察组和对照组,每组各50例,对照组患者给予人工流产,观察组在对照组的基础上术前口服米非司酮,观察并比较两组患者早孕绒毛CD4+、CD8+水平及细胞因子的差异。结果观察组患者的CD4+\CD4+/CD8+分别为(30.8±2.6)、(1.41±0.22)明显高于对照组(24.9±2.4)、(1.38±0.20),差异有统计学意义(P<0.05),而CD8+观察组为(20.2±1.9),对照组为(20.1±2.7),与对照组比较,差异无统计学意义(P>0.05)。观察组患者TGF-β(22.18±5.21)低于对照组(26.63±6.43),观察组患者TNF-α(27.25±3.52)高于对照组(21.56±6.58),差异有统计学意义(P<0.05)。结论人工流产术前口服米非司酮可升高患者的CD4+,对CD8+无明显影响。
目的:探討米非司酮對早孕絨毛CD4+、CD8+及細胞因子的影響。方法將本院2012年5月-2013年12月本院收治的100例早孕流產患者分為觀察組和對照組,每組各50例,對照組患者給予人工流產,觀察組在對照組的基礎上術前口服米非司酮,觀察併比較兩組患者早孕絨毛CD4+、CD8+水平及細胞因子的差異。結果觀察組患者的CD4+\CD4+/CD8+分彆為(30.8±2.6)、(1.41±0.22)明顯高于對照組(24.9±2.4)、(1.38±0.20),差異有統計學意義(P<0.05),而CD8+觀察組為(20.2±1.9),對照組為(20.1±2.7),與對照組比較,差異無統計學意義(P>0.05)。觀察組患者TGF-β(22.18±5.21)低于對照組(26.63±6.43),觀察組患者TNF-α(27.25±3.52)高于對照組(21.56±6.58),差異有統計學意義(P<0.05)。結論人工流產術前口服米非司酮可升高患者的CD4+,對CD8+無明顯影響。
목적:탐토미비사동대조잉융모CD4+、CD8+급세포인자적영향。방법장본원2012년5월-2013년12월본원수치적100례조잉유산환자분위관찰조화대조조,매조각50례,대조조환자급여인공유산,관찰조재대조조적기출상술전구복미비사동,관찰병비교량조환자조잉융모CD4+、CD8+수평급세포인자적차이。결과관찰조환자적CD4+\CD4+/CD8+분별위(30.8±2.6)、(1.41±0.22)명현고우대조조(24.9±2.4)、(1.38±0.20),차이유통계학의의(P<0.05),이CD8+관찰조위(20.2±1.9),대조조위(20.1±2.7),여대조조비교,차이무통계학의의(P>0.05)。관찰조환자TGF-β(22.18±5.21)저우대조조(26.63±6.43),관찰조환자TNF-α(27.25±3.52)고우대조조(21.56±6.58),차이유통계학의의(P<0.05)。결론인공유산술전구복미비사동가승고환자적CD4+,대CD8+무명현영향。
Objective To explore the influence of mifepristone on CD4+,CD8+ and cytokines of chorionic villi. Methods 100 pa-tients with pregnancy abortion were treated in our hospital from May, 2012 to December 2013,they were divided into the observa-tion group and control group, each group of 50 cases, the control group was given abortion treated, and the observation group was given the mifepristone treated on the basis of the control group, the difference of CD4+,CD8+ and cytokines in chorionic villi of the two groups were compared. Results The observation group of patients with CD4+\ CD4+/ CD8+ were (30.8±2.6), (1.41±0.22) was significantly higher than the control group (24.9±2.4), (1.38±0.20), the difference was statistically significant (P<0.05),while CD8+treatment group was (20.2±1.9), control group (20.1±2.7), compared with the control group, no significant difference (P>0.05). The patients in observation group TGF-beta (22.18±5.21) lower than that of the control group (26.63±6.43), the patients in obser-vation group TNF- α (27.25±3.52) higher than that of the control group (21.56±6.58), the difference was statistically significant (P<0.05). Conclusion Abortion preoperative oral mifepristone can be elevated in patients with CD4 +, but has no obvious effect on CD8+.