中国医药导报
中國醫藥導報
중국의약도보
CHINA MEDICAL HERALD
2014年
18期
151-154
,共4页
妊娠期高血压疾病%新生儿心肌损伤%心肌酶检测
妊娠期高血壓疾病%新生兒心肌損傷%心肌酶檢測
임신기고혈압질병%신생인심기손상%심기매검측
Hypertensive disorder complicating pregnancy%Neonatal myocardial injury%Enzyme detection
目的：通过检测妊娠高血压疾病(HDCP)母亲所生新生儿的肌钙蛋白(cTnT)水平,对比分析新生儿心肌损害与HDCP的关系.方法选择55例HDCP母亲所生新生儿为研究组,根据母亲患病情况将其分为轻度组34例,重度组21例.选择同期健康母亲所生新生儿30例为对照组,检测并比较各组治疗前后cTnT水平变化情况及心肌损伤率.结果轻度组、重度组心肌及对照组cTnT水平分别为(110.58±35.55)、(182.84±72.77)、(64.35±22.41)μg/L,三组比较差异统计学意义(P<0.05)；重度组患儿心肌损伤率(76.2%)明显高于轻度组(54.2豫),差异统计学意义(P<0.05).治疗后,轻度组和重度组cTnT水平均明显降低,差异均有统计学意义(P<0.05).结论 HDCP母亲所生新生儿心肌损伤发生率明显高于健康母亲的新生儿,在临床中应高度重视妊娠高血压对新生儿的影响,及早行心肌酶检测,保护新生儿心功能,可有效预防并发症。
目的：通過檢測妊娠高血壓疾病(HDCP)母親所生新生兒的肌鈣蛋白(cTnT)水平,對比分析新生兒心肌損害與HDCP的關繫.方法選擇55例HDCP母親所生新生兒為研究組,根據母親患病情況將其分為輕度組34例,重度組21例.選擇同期健康母親所生新生兒30例為對照組,檢測併比較各組治療前後cTnT水平變化情況及心肌損傷率.結果輕度組、重度組心肌及對照組cTnT水平分彆為(110.58±35.55)、(182.84±72.77)、(64.35±22.41)μg/L,三組比較差異統計學意義(P<0.05)；重度組患兒心肌損傷率(76.2%)明顯高于輕度組(54.2豫),差異統計學意義(P<0.05).治療後,輕度組和重度組cTnT水平均明顯降低,差異均有統計學意義(P<0.05).結論 HDCP母親所生新生兒心肌損傷髮生率明顯高于健康母親的新生兒,在臨床中應高度重視妊娠高血壓對新生兒的影響,及早行心肌酶檢測,保護新生兒心功能,可有效預防併髮癥。
목적：통과검측임신고혈압질병(HDCP)모친소생신생인적기개단백(cTnT)수평,대비분석신생인심기손해여HDCP적관계.방법선택55례HDCP모친소생신생인위연구조,근거모친환병정황장기분위경도조34례,중도조21례.선택동기건강모친소생신생인30례위대조조,검측병비교각조치료전후cTnT수평변화정황급심기손상솔.결과경도조、중도조심기급대조조cTnT수평분별위(110.58±35.55)、(182.84±72.77)、(64.35±22.41)μg/L,삼조비교차이통계학의의(P<0.05)；중도조환인심기손상솔(76.2%)명현고우경도조(54.2예),차이통계학의의(P<0.05).치료후,경도조화중도조cTnT수평균명현강저,차이균유통계학의의(P<0.05).결론 HDCP모친소생신생인심기손상발생솔명현고우건강모친적신생인,재림상중응고도중시임신고혈압대신생인적영향,급조행심기매검측,보호신생인심공능,가유효예방병발증。
Objective To contrastive analyze the relationship between neonatal myocardial damage and hypertensive disorder complicating pregnancy (HDCP) by the detecting of cTnT levels of newborns born to mothers with HDCP. Methods 55 infants born to mothers with HDCP were selected as study group, and they were divided into mild group (34 cases) and severe group (21 cases). 30 newborns born to healthy mothers in same period were selected as control group. The levels of cTnT before and after the trenament and the rate of myocardial injury were detected and compared. Results The level of cTnT in mild group, severe group, and control group were(110.58±35.55),(182.84±72.77),(64.35±22.41)μg/L respectively, the differences of three groups were statistically significant (P<0.05);the rate of myocardial injury in severe group (76.2%) was higher than that of the control group(54.2%), the difference was statistically signif-icant (P< 0.05). The level of cTnT in mild group and severe group were significantly decreased after treatment com-pared with before treatment, the difference was statistically significant (P<0.05). Conclusion The incidence of myocar-dial injury in newborn born to mothers with HDCP is significantly higher than that of the newborn born to healthy mother, should attach great importance to the influence of gestational hypertension on the newborn in the clinical, test the myocardial enzyme early, protect the cardiac function of neonatal, can prevent the complications effectively.
