现代中西医结合杂志
現代中西醫結閤雜誌
현대중서의결합잡지
MODERN JOURNAL OF INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE
2014年
18期
1948-1949,1953
,共3页
胡宏章%车辉娟%唐虹%张焕强%王军荐%姜桂容%严薛丹
鬍宏章%車輝娟%唐虹%張煥彊%王軍薦%薑桂容%嚴薛丹
호굉장%차휘연%당홍%장환강%왕군천%강계용%엄설단
急性心肌梗死%反应蛋白%肌钙蛋白 T
急性心肌梗死%反應蛋白%肌鈣蛋白 T
급성심기경사%반응단백%기개단백 T
acute myocardial infarction%C - reactive protein%cardiac troponin T
目的:探讨血清 C 反应蛋白(CRP)和心肌肌钙蛋白 T( cTnT)在诊治急性心肌梗死(AMI)患者中的临床应用价值和意义。方法选择67例 AMI 患者(观察组)、51例非心血管疾病患者(对照组)及健康体检人群56例(健康对照组),分别测定 CRP 和 cTnT 水平并进行比较。结果观察组 CRP 及 cTnT 检测阳性率分别为82%和84%,对照组分别为6%和0,健康对照组分别为5%和0,观察组与对照组和健康对照组比较有显著性差异( P 均﹤0.01),对照组与健康对照组比较无显著性差异(P ﹥0.05)。观察组 cTnT 与 CRP 水平显著正相关(r =0.982,P ﹤0.01)。观察组 CRP、cTnT 单独检测时,其敏感度、特异度分别为82%,90%和84%,100%;联合应用两者后其敏感度为88%,特异度91%。结论 cTnl 与 CRP 对 AMI的诊断及早期诊断具有重要的临床应用价值,值得临床推广应用。
目的:探討血清 C 反應蛋白(CRP)和心肌肌鈣蛋白 T( cTnT)在診治急性心肌梗死(AMI)患者中的臨床應用價值和意義。方法選擇67例 AMI 患者(觀察組)、51例非心血管疾病患者(對照組)及健康體檢人群56例(健康對照組),分彆測定 CRP 和 cTnT 水平併進行比較。結果觀察組 CRP 及 cTnT 檢測暘性率分彆為82%和84%,對照組分彆為6%和0,健康對照組分彆為5%和0,觀察組與對照組和健康對照組比較有顯著性差異( P 均﹤0.01),對照組與健康對照組比較無顯著性差異(P ﹥0.05)。觀察組 cTnT 與 CRP 水平顯著正相關(r =0.982,P ﹤0.01)。觀察組 CRP、cTnT 單獨檢測時,其敏感度、特異度分彆為82%,90%和84%,100%;聯閤應用兩者後其敏感度為88%,特異度91%。結論 cTnl 與 CRP 對 AMI的診斷及早期診斷具有重要的臨床應用價值,值得臨床推廣應用。
목적:탐토혈청 C 반응단백(CRP)화심기기개단백 T( cTnT)재진치급성심기경사(AMI)환자중적림상응용개치화의의。방법선택67례 AMI 환자(관찰조)、51례비심혈관질병환자(대조조)급건강체검인군56례(건강대조조),분별측정 CRP 화 cTnT 수평병진행비교。결과관찰조 CRP 급 cTnT 검측양성솔분별위82%화84%,대조조분별위6%화0,건강대조조분별위5%화0,관찰조여대조조화건강대조조비교유현저성차이( P 균﹤0.01),대조조여건강대조조비교무현저성차이(P ﹥0.05)。관찰조 cTnT 여 CRP 수평현저정상관(r =0.982,P ﹤0.01)。관찰조 CRP、cTnT 단독검측시,기민감도、특이도분별위82%,90%화84%,100%;연합응용량자후기민감도위88%,특이도91%。결론 cTnl 여 CRP 대 AMI적진단급조기진단구유중요적림상응용개치,치득림상추엄응용。
Objective It is to approach the clinical application Values and meaning of cardiac troponin T(cTnT)and C -reactive protein(CRP)in patients with acute myocardial infarction(AMI). Methods The plasma cTnT and CRP were detec-ted and compared in 67 patients with AMI(observation group),51 patients excluding cardiovascular diseases(control group) and 56 healthy people(healthy control group). Results The positive rate of cTnT and CRP was 82% and 84% in observation group,6% and 0 in control group,5% and 0 in healthy control group. There was significant difference between observation group and control group or healthy control group(all P ﹤ 0. 01),there was no significant difference between control group and healthy control group(P ﹥ 0. 05). There was significant positive correlation between cTnT and CRP in observation group(r =0. 982,P ﹤ 0. 01). For the separate test of cTnT and CRP in observation group,sensitivity were 82% and 90% respectively, specificity were 84% and 100% respectively. The specificity and sensitivity of the two combined application were 91% and 88% respectively. Conclusion The detections of cTnT and CRP have very important clinical value in diagnosis and early diag-nosis of AMI,it is worth for clinical use application.