CAJ | 학술논문

目的：分析结核抗体检测在小儿结核病诊断中的应用效果。方法选择本地区2012-2013年收治的结核病患儿患48例为观察组，并以同期入院的非结核病患儿35例为对照组，并对两组患儿的体液标本涂片、卡介菌纯化蛋白衍生物（PPD）和结核抗体检测结果进行比较。结果三种方法组间差异具有统计学意义，其中以PPD法阳性率最高达68.8%，涂片法最低（27.0%）；不同类型结核检测结果方面：涂片法肺结核的阳性率显著高于肺外结核（P<0.05），而PPD法和结核抗体法在肺结核和肺外结核的阳性率方面差异均不显著（P>0.05）。结论结核抗体检测、涂片法和PPD检测在结核病诊断中各有特色，其中结核抗体检测尤其适于作为儿童、肺外结核及无痰患者的快速辅助诊断手段。
목적：분석결핵항체검측재소인결핵병진단중적응용효과。방법선택본지구2012-2013년수치적결핵병환인환48례위관찰조，병이동기입원적비결핵병환인35례위대조조，병대량조환인적체액표본도편、잡개균순화단백연생물（PPD）화결핵항체검측결과진행비교。결과삼충방법조간차이구유통계학의의，기중이PPD법양성솔최고체68.8%，도편법최저（27.0%）；불동류형결핵검측결과방면：도편법폐결핵적양성솔현저고우폐외결핵（P<0.05），이PPD법화결핵항체법재폐결핵화폐외결핵적양성솔방면차이균불현저（P>0.05）。결론결핵항체검측、도편법화PPD검측재결핵병진단중각유특색，기중결핵항체검측우기괄우작위인동、폐외결핵급무담환자적쾌속보조진단수단。
Objective To investigate the application of tuberculosis antibody in diagnosis of children with tuberculosis. Methods 48 patients with tuberculosis of our area from 2012 to 2013 were selected as observation group, and other 35 patients without tu-berculosis were as control, and the results of humoral smear, PPD and tuberculosis antibody detection were compared of two groups. Results There were significantly difference between three methods, and the positive rate of PPD was 68.8%,higher than humoral smear(27.0%); Results of different types of TB:the positive rate of tuberculosis were higher than extrapulmonary tubercu-losis by humoral smear(P<0.05), and there was no difference between PPD and tuberculosis antibody method in diagnosis of differ-ent types of TB. Conclusion Humoral smear, PPD and tuberculosis antibody detection all have its virtue in the diagnosis of tuber-culosis, and the tuberculosis antibody detection especially fit as a quick diagnosis tool for children, extrapulmonary tuberculosis and patients without sputum.