国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
10期
1419-1421
,共3页
曹伟胜%陈少南%钟群珍%黎灿然%黄剑甫
曹偉勝%陳少南%鐘群珍%黎燦然%黃劍甫
조위성%진소남%종군진%려찬연%황검보
包皮龟头炎%真菌%念珠菌%药敏试验
包皮龜頭炎%真菌%唸珠菌%藥敏試驗
포피구두염%진균%념주균%약민시험
Balanoposthitis%Fungi%Candida%Susceptibility test
目的 了解本地区包皮龟头炎患者中真菌感染情况及对抗生素的敏感性.方法 分别采用科玛嘉念珠菌显色培养基、法国梅里埃公司的ATB ID32C酵母菌鉴定卡和Rosco纸片扩散法对包皮龟头分泌物进行念珠菌培养、菌种鉴定及药敏试验.结果 458例患者中共培养出157株酵母样真菌,阳性率为34.3％;其中,白色念珠菌116株(73.9％),光滑念珠菌14株(8.9％),热带念珠菌12株(7.6％),近平滑念珠菌8株(5.1％),克柔念珠菌5株(3.2％),季也蒙念珠菌2株(1.3％).分离菌株对制霉菌素和酮康唑的敏感率均＞90.0％,分别为97.5％和93.0％,对氟康唑敏感率为79.6％,而对特比奈酚敏感性最低,为33.8％.结论 念珠菌感染是本地区包皮龟头炎发病的重要因素,感染的致病菌种以白色念珠菌为主,分离的念珠菌对多烯类药物敏感率较高,对唑类抗真菌药有不同程度的交叉耐药,不同菌型其药敏谱存在差异.
目的 瞭解本地區包皮龜頭炎患者中真菌感染情況及對抗生素的敏感性.方法 分彆採用科瑪嘉唸珠菌顯色培養基、法國梅裏埃公司的ATB ID32C酵母菌鑒定卡和Rosco紙片擴散法對包皮龜頭分泌物進行唸珠菌培養、菌種鑒定及藥敏試驗.結果 458例患者中共培養齣157株酵母樣真菌,暘性率為34.3％;其中,白色唸珠菌116株(73.9％),光滑唸珠菌14株(8.9％),熱帶唸珠菌12株(7.6％),近平滑唸珠菌8株(5.1％),剋柔唸珠菌5株(3.2％),季也矇唸珠菌2株(1.3％).分離菌株對製黴菌素和酮康唑的敏感率均＞90.0％,分彆為97.5％和93.0％,對氟康唑敏感率為79.6％,而對特比奈酚敏感性最低,為33.8％.結論 唸珠菌感染是本地區包皮龜頭炎髮病的重要因素,感染的緻病菌種以白色唸珠菌為主,分離的唸珠菌對多烯類藥物敏感率較高,對唑類抗真菌藥有不同程度的交扠耐藥,不同菌型其藥敏譜存在差異.
목적 료해본지구포피구두염환자중진균감염정황급대항생소적민감성.방법 분별채용과마가념주균현색배양기、법국매리애공사적ATB ID32C효모균감정잡화Rosco지편확산법대포피구두분비물진행념주균배양、균충감정급약민시험.결과 458례환자중공배양출157주효모양진균,양성솔위34.3％;기중,백색념주균116주(73.9％),광활념주균14주(8.9％),열대념주균12주(7.6％),근평활념주균8주(5.1％),극유념주균5주(3.2％),계야몽념주균2주(1.3％).분리균주대제매균소화동강서적민감솔균＞90.0％,분별위97.5％화93.0％,대불강서민감솔위79.6％,이대특비내분민감성최저,위33.8％.결론 념주균감염시본지구포피구두염발병적중요인소,감염적치병균충이백색념주균위주,분리적념주균대다희류약물민감솔교고,대서류항진균약유불동정도적교차내약,불동균형기약민보존재차이.
Objective To understand the fungal infection and antibiotic susceptibility in patients with balanoposthitis in Zhaoqing.Methods CHROM agar candida,ATB ID32C of France Bio-Merieux Company and Rosco Disk diffusion method were applied to culture and identify candida strains and for yeast susceptibility testing.Results 157 cases(34.3％) were infected by candida in the 458 patients; of which,116 (73.9％) were infected by candida albicans,14 (8.9％) by candida glabrata,12 (7.6％) by candida tropicalis,8 (5.1％) by candida parapsilosis,5 (3.2％) by candida krusei,and 2 (1.3％) by candida guilliermondii.The susceptibility rate of the isolated strains to nystatin and ketoconazole were both more than 90.0％,97.5％ and 93.0％,respectively.The susceptibility rate to fluconazole was 79.6％,while the susceptibility rate to terbinafine was lowest,33.8％.Conclusions Candida infection is the most important pathogenetic factor for balanoposthitis and the main species of pathogenetic yeasts is candida albicans in Zhaoqing area.Candida have a higher drug susceptibility rate to polyene drugs and have different degree of cross resistance to azole drugs.There are differences among the antibiotic sensitivity spectrums of various candida.
