河北医科大学学报
河北醫科大學學報
하북의과대학학보
JOURNAL OF HEBEI MEDICAL UNIVERSITY
2014年
5期
556-559
,共4页
特发性肺纤维化%肺疾病,间质性%诊断,鉴别
特髮性肺纖維化%肺疾病,間質性%診斷,鑒彆
특발성폐섬유화%폐질병,간질성%진단,감별
idiopathic pulmonary fibrosis%lung diseases,interstitial%diagnnosis differential
目的：探讨特发性肺间质纤维化（ idiopathic pulmonary fibrosis，IPF）与结缔组织病相关间质性肺疾病（ connective tissues disease-interstitial lung disease，CTD-ILD）高分辨率CT（ high resolution CT，HRCT）征象的不同特点及应用价值。方法回顾性分析经HRCT扫描的17例IPF患者和36例CTD-ILD患者，根据磨玻璃密度影及实变影、蜂窝、小叶内间质增厚、牵拉支气管扩张、胸膜下曲线及小叶间隔增厚、胸膜增厚、胸腔积液、纵隔淋巴结增大的HRCT征象进行统计学分析。结果蜂窝是IPF的主要征象占64.7％，而CTD-ILD占16.7％（P＝0.003）。磨玻璃影和实变影是CTD-ILD的主要征象占72.2％，而IPF占29.4％（P＝0.000）。牵拉支气管扩张多见于IPF中占41.2％，CTD-ILD占13.9％（P＝0.027）。结论虽然IPF的HRCT征象与CTD-ILD有许多相同或相似之处，但是IPF患者肺间质纤维化的进展程度明显超过CTD-ILD。
目的：探討特髮性肺間質纖維化（ idiopathic pulmonary fibrosis，IPF）與結締組織病相關間質性肺疾病（ connective tissues disease-interstitial lung disease，CTD-ILD）高分辨率CT（ high resolution CT，HRCT）徵象的不同特點及應用價值。方法迴顧性分析經HRCT掃描的17例IPF患者和36例CTD-ILD患者，根據磨玻璃密度影及實變影、蜂窩、小葉內間質增厚、牽拉支氣管擴張、胸膜下麯線及小葉間隔增厚、胸膜增厚、胸腔積液、縱隔淋巴結增大的HRCT徵象進行統計學分析。結果蜂窩是IPF的主要徵象佔64.7％，而CTD-ILD佔16.7％（P＝0.003）。磨玻璃影和實變影是CTD-ILD的主要徵象佔72.2％，而IPF佔29.4％（P＝0.000）。牽拉支氣管擴張多見于IPF中佔41.2％，CTD-ILD佔13.9％（P＝0.027）。結論雖然IPF的HRCT徵象與CTD-ILD有許多相同或相似之處，但是IPF患者肺間質纖維化的進展程度明顯超過CTD-ILD。
목적：탐토특발성폐간질섬유화（ idiopathic pulmonary fibrosis，IPF）여결체조직병상관간질성폐질병（ connective tissues disease-interstitial lung disease，CTD-ILD）고분변솔CT（ high resolution CT，HRCT）정상적불동특점급응용개치。방법회고성분석경HRCT소묘적17례IPF환자화36례CTD-ILD환자，근거마파리밀도영급실변영、봉와、소협내간질증후、견랍지기관확장、흉막하곡선급소협간격증후、흉막증후、흉강적액、종격림파결증대적HRCT정상진행통계학분석。결과봉와시IPF적주요정상점64.7％，이CTD-ILD점16.7％（P＝0.003）。마파리영화실변영시CTD-ILD적주요정상점72.2％，이IPF점29.4％（P＝0.000）。견랍지기관확장다견우IPF중점41.2％，CTD-ILD점13.9％（P＝0.027）。결론수연IPF적HRCT정상여CTD-ILD유허다상동혹상사지처，단시IPF환자폐간질섬유화적진전정도명현초과CTD-ILD。
Objective To evaluate the difference and the diagnostic value of high-resolution CT (HRCT)findings in patients with idiopathic pulmonary fibrosis(idiopathic pulmonary fibrosis,IPF)and connective tissues disease-interstitial lung disease( connective tissues disease-interstitial lung disease, CTD-ILD). Methods Seventeen patients with IPF and 36 patients with CTD-ILD scanned by HRCT were reviewed retrospectively. Statistical analysis was conducted in ground-glass opacity and consolidation,honeycombing,interlobular interstitial thickening,traction bronchiectasis,subpleural curve and interlobular septal thickening,pleural thickening,pleural effusion and meditational lymph node enlargement. Results Honeycombing was the predominant pattern(64. 7%)in IPF,while CTD-ILD only accounted for 16 . 7%( P =0 . 003 ). Ground-glass opacity and consolidation was the predominant pattern in CTD-ILD(72. 2%),while IPF accounted just for 29. 4%(P=0. 000). Traction bronchiectasis was 41. 2% in IPF,but 13. 9% in CTD-ILD(P=0. 027). Conclusion Although HRCT findings of IPF and CTD-ILD are similar and overlap considerably,but patients with IPF showed a tendency to more progressed fibrosis than patients with CTD-ILD.
