CAJ | 학술논문

目的：比较腹腔镜和开腹手术治疗早期卵巢癌的疗效。方法回顾性分析2009年1月～2013年12月我院手术治疗的早期卵巢癌48例，其中腹腔镜手术25例（腹腔镜组），开腹手术23例（开腹组），比较2组手术时间、术中出血量、术后住院时间、肛门排气时间、术后并发症及切口感染率等。结果腹腔镜组术中出血量（150．2±50．8）ml，明显少于开腹组（235．6±49．3）ml（t＝-5．901，P＝0．000）；腹腔镜组术后肛门排气时间（36．2±13．5）h，明显早于开腹组（48．3±13．9）h （t＝-3．058，P＝0．004）；腹腔镜组术后发热6例，显著少于开腹组12例（χ2＝4．057，P＝0．044）；腹腔镜组术后切口感染2例，与开腹组6例无统计学差异（χ2＝1．670，P＝0．196）；腹腔镜组住院时间（15．2±5．2） d，明显短于开腹组（23．3±4．2） d （t＝5．904，P＝0.000）。2组手术时间分别为（241．4±45．3）、（248．5±58．3）min，无统计学差异（t＝-0．473，P＝0．638）；2组切除淋巴结分别（21．3±2．9）、（20．5±3．0）枚，无统计学差异（t＝0．939，P＝0．353）。45例（开腹组2例失访，腹腔镜组1例失访）随访1～52个月，平均21．5月。开腹组2例分别术后10、12个月复发，腹腔镜组1例术后10个月复发，其余无瘤生存。结论腹腔镜手术治疗早期卵巢癌近期疗效好，安全可行，可作为早期卵巢癌手术治疗的新选择。
목적：비교복강경화개복수술치료조기란소암적료효。방법회고성분석2009년1월～2013년12월아원수술치료적조기란소암48례，기중복강경수술25례（복강경조），개복수술23례（개복조），비교2조수술시간、술중출혈량、술후주원시간、항문배기시간、술후병발증급절구감염솔등。결과복강경조술중출혈량（150．2±50．8）ml，명현소우개복조（235．6±49．3）ml（t＝-5．901，P＝0．000）；복강경조술후항문배기시간（36．2±13．5）h，명현조우개복조（48．3±13．9）h （t＝-3．058，P＝0．004）；복강경조술후발열6례，현저소우개복조12례（χ2＝4．057，P＝0．044）；복강경조술후절구감염2례，여개복조6례무통계학차이（χ2＝1．670，P＝0．196）；복강경조주원시간（15．2±5．2） d，명현단우개복조（23．3±4．2） d （t＝5．904，P＝0.000）。2조수술시간분별위（241．4±45．3）、（248．5±58．3）min，무통계학차이（t＝-0．473，P＝0．638）；2조절제림파결분별（21．3±2．9）、（20．5±3．0）매，무통계학차이（t＝0．939，P＝0．353）。45례（개복조2례실방，복강경조1례실방）수방1～52개월，평균21．5월。개복조2례분별술후10、12개월복발，복강경조1례술후10개월복발，기여무류생존。결론복강경수술치료조기란소암근기료효호，안전가행，가작위조기란소암수술치료적신선택。
Objective To compare the efficacy of laparoscopic and open surgery for early-stag ovarian cancer ( EOC ) . Methods Outcomes of 48 patients with EOC who underwent either laparoscopic surgery ( laparoscopic surgery group , n=25) or open surery (open surgery group, n=23) from January 2009 to December 2013 were retrospectively analyzed.The intraoperative parameters and postoperative complications were compared between the two groups . Results The laparoscopic surgery group had significantly less intraoperative blood loss [(150.2 ±50.8) ml vs.(235.6 ±49.3) ml, t =-5.901, P =0.000], shorter recovery time of gastrointestinal function [(36.2 ±13.5) h vs.(48.3 ±13.9) h,t=-3.058, P=0.004], fewer postoperative fever (6 cases vs.12 cases,χ2 =4.057, P=0.044), fewer postoperative incision infections (2 cases vs.6 cases, χ2 =1.670, P=0.196), and shorter postoperative hospital stay [(15.2 ±5.2)d vs.(23.3 ±4.2) d,t=5.904, P=0.000] than those in the open surgery group, respectively.No significant difference was detected in the operation time [(241.4 ±45.3) min vs.(248.5 ±58.3) min, t =-0.473, P=0.638] and the number of lymph node removed [(21.3 ±2.9) vs.(20.5 ±3.0),t=0.939, P=0.353] between the two groups.A total of 45 patients were followed up for 1-52 months, with an average of 21.5 months.Recurrence was recorded in 2 cases in the laparoscopic surgery group (10 months and 12 months after operation) and in 1 case (10 months after operation) in the open surgery group .The remaining cases obtaied disease-free survival . Conclusion Laparoscopic surgery in the treatment of EOC has a good short-term efficacy,and can be used as a new choice for the operative treatment of EOC .