武警医学
武警醫學
무경의학
MEDICAL JOURNAL OF THE CHINESE PEOPLE'S ARMED POLICE FORCES
2014年
7期
720-723
,共4页
赵卫东%宁健%赵水喜%孙化冬%穆晓峰
趙衛東%寧健%趙水喜%孫化鼕%穆曉峰
조위동%저건%조수희%손화동%목효봉
Grave’s眼病%调强放射治疗%放射治疗计划,计算机辅助
Grave’s眼病%調彊放射治療%放射治療計劃,計算機輔助
Grave’s안병%조강방사치료%방사치료계화,계산궤보조
Grave’ s ophthalmopathy%intensity modulated radiotherapy%treatment planning,computer-assisted
目的：探讨三维适形（含电子线照射野）的照射技术治疗双眶Grave’s眼病的实施方法及其剂量学优势。方法10例确诊为双侧Grave’ s眼病的患者，均用三维适形（含电子线照射野）照射技术、传统的对穿野照射技术以及近年来主流的调强照射技术等三种技术完成治疗计划，比较计划靶区（planning target volume，PTV）和危及器官（organ at risk，OAR）的剂量分布图、剂量体积直方图和剂量学参数。结果对于PTV的参数D98％、V95％、Dmean、CI和HI，双侧晶体的参数Dmin、Dmean和Dmax，双侧泪腺的参数Dmin和Dmean，三维适形和调强技术二者与对穿野技术相比差异均具有统计学意义（P＜0．05），但三维适形与调强技术相比差异无统计学意义。对于PTV的参数D2％和双侧泪腺的参数Dmax，则三种技术之间比较差异均无统计学意义。结论三维适形（含电子线照射野）和调强技术与传统的对穿野技术相比都有着同样的剂量学优势，在患者不愿意接受调强技术昂贵的价格或者没有调强设备的时候，可以用三维适形技术代替。
目的：探討三維適形（含電子線照射野）的照射技術治療雙眶Grave’s眼病的實施方法及其劑量學優勢。方法10例確診為雙側Grave’ s眼病的患者，均用三維適形（含電子線照射野）照射技術、傳統的對穿野照射技術以及近年來主流的調彊照射技術等三種技術完成治療計劃，比較計劃靶區（planning target volume，PTV）和危及器官（organ at risk，OAR）的劑量分佈圖、劑量體積直方圖和劑量學參數。結果對于PTV的參數D98％、V95％、Dmean、CI和HI，雙側晶體的參數Dmin、Dmean和Dmax，雙側淚腺的參數Dmin和Dmean，三維適形和調彊技術二者與對穿野技術相比差異均具有統計學意義（P＜0．05），但三維適形與調彊技術相比差異無統計學意義。對于PTV的參數D2％和雙側淚腺的參數Dmax，則三種技術之間比較差異均無統計學意義。結論三維適形（含電子線照射野）和調彊技術與傳統的對穿野技術相比都有著同樣的劑量學優勢，在患者不願意接受調彊技術昂貴的價格或者沒有調彊設備的時候，可以用三維適形技術代替。
목적：탐토삼유괄형（함전자선조사야）적조사기술치료쌍광Grave’s안병적실시방법급기제량학우세。방법10례학진위쌍측Grave’ s안병적환자，균용삼유괄형（함전자선조사야）조사기술、전통적대천야조사기술이급근년래주류적조강조사기술등삼충기술완성치료계화，비교계화파구（planning target volume，PTV）화위급기관（organ at risk，OAR）적제량분포도、제량체적직방도화제량학삼수。결과대우PTV적삼수D98％、V95％、Dmean、CI화HI，쌍측정체적삼수Dmin、Dmean화Dmax，쌍측루선적삼수Dmin화Dmean，삼유괄형화조강기술이자여대천야기술상비차이균구유통계학의의（P＜0．05），단삼유괄형여조강기술상비차이무통계학의의。대우PTV적삼수D2％화쌍측루선적삼수Dmax，칙삼충기술지간비교차이균무통계학의의。결론삼유괄형（함전자선조사야）화조강기술여전통적대천야기술상비도유착동양적제량학우세，재환자불원의접수조강기술앙귀적개격혹자몰유조강설비적시후，가이용삼유괄형기술대체。
Objective To study the implementation and dosimetric advantages of three-dimensional conformal irradiation (3DCRT) including electron beam irradiation field in the treatment of bilateral Grave ’ s ophthalmopathy .Methods All the ten pa-tients diagnosed as having bilateral Grave ’ s ophthalmopathy were scheduled for such three techniques including three -dimensional con-formal irradiation , the conventional opposing field irradiation ( OF) and the mainstream intensity modulated irradiation ( IMRT) in re-cent years .Dose distribution diagrams , dose volume histograms and dosimetric parameters of the planning target volume ( PTV) and or-gans at risk (OARs) were compared.Results For D98%,V95%,Dmean, CI and HI in PTV parameters, Dmin, Dmean and Dmax in bilateral lens parameters , Dmin,Dmean in bilateral lacrimal glands parameters , 3DCRT and IMRT compared with OF were statisti-cally significantly different (P<0.05), while no significant difference was found between 3DCRT and IMRT technique,for D2% in PTV parameters and Dmax in bilateral lacrimal glands parameters , the comparison between such three technologies were not statistically significantly different (P>0.05).Conclusions 3DCRT (including electron beam irradiation field ) and IMRT technology have as many dosimetric advantages as OF technology .This technology can replace IMRT technology if patients are unwilling to accept IMRT due to its price or no IMRT equipment can be acquired .
