CAJ | 학술논문

目的：探讨宫颈癌患者采用放射治疗疗效及影响放疗预后的相关因素。方法回顾性分析178例宫颈癌患者的临床资料，观察放疗效果及并发症发生情况，同时分析患者年龄，FIGO分期，病理类型、肿瘤大小、分化程度及血红蛋白水平与放疗预后的关系。结果178例患者1年生存率为84．27％（150/178），3年生存率为70．22％（125/178）。宫颈癌患者放疗的预后与年龄、病理分级、肿瘤直径、FIGO分期及血红蛋白含量有关，（χ2＝6．73，10．57，11．95，12．76，11．41，P均＜0．05）。178例患者中，19例发生放射性直肠炎，12例发生放射性膀胱炎，2例患者因直肠穿孔及小肠梗阻死亡，晚期并发症的发生率占18．54％。结论宫颈癌患者外照射及适型强调放疗疗效确切，其预后与多肿瘤分期、分化程度及是否分血等多种因素有关，可采取相应的干预措施提高放疗效果。
목적：탐토궁경암환자채용방사치료료효급영향방료예후적상관인소。방법회고성분석178례궁경암환자적림상자료，관찰방료효과급병발증발생정황，동시분석환자년령，FIGO분기，병리류형、종류대소、분화정도급혈홍단백수평여방료예후적관계。결과178례환자1년생존솔위84．27％（150/178），3년생존솔위70．22％（125/178）。궁경암환자방료적예후여년령、병리분급、종류직경、FIGO분기급혈홍단백함량유관，（χ2＝6．73，10．57，11．95，12．76，11．41，P균＜0．05）。178례환자중，19례발생방사성직장염，12례발생방사성방광염，2례환자인직장천공급소장경조사망，만기병발증적발생솔점18．54％。결론궁경암환자외조사급괄형강조방료료효학절，기예후여다종류분기、분화정도급시부분혈등다충인소유관，가채취상응적간예조시제고방료효과。
Objective To investigate the efficacy of radiotherapy for cervical cancer and related prognostic factors . Methods Clinical data of 178 cases of cervical cancer were retrospectively analyzed .Efficacy and complications were observed , and relation of prognosis and age ,FIGO stage,pathological type ,tumor size,degree of differentiation ,and hemoglobin levels were analyzed.Results Among 178 patients,1-year survival rate was 84.27%(150/178),3-year survival rate was 70.22% (125/178).The prognosis of patients with cervical cancer radiotherapy with age ,tumor grade,tumor size,FIGO stage and hemoglobin content were relevant,(χ2 =6.73,10.57,11.95,12.76,11.41,all P<0.05).In 178 patients,19 cases had radiation proctitis, 12 cases had radiation cystitis ,2 patients died due to rectal perforation and small bowel obstruction , the incidence of advanced complications accounted for 18.54%.Conclusion Conformal external beam radiotherapy for cervical cancer patients is effec-tive,prognosis was related with tumor stage and more variety of factors ,and degree of differentiation of blood ,appropriate interven-tions should be taken to improve the effectiveness of radiotherapy .