实用癌症杂志
實用癌癥雜誌
실용암증잡지
THE PRACTICAL JOURNAL OF CANCER
2014年
7期
799-801
,共3页
王乐%李午平%黄燕
王樂%李午平%黃燕
왕악%리오평%황연
非霍奇金淋巴瘤%CD4/CD8值%化疗%近期疗效
非霍奇金淋巴瘤%CD4/CD8值%化療%近期療效
비곽기금림파류%CD4/CD8치%화료%근기료효
Non-Hodgkin’s lymphoma%CD4/CD8%Chemotherapy%Short term effect
目的:分析非霍奇金淋巴瘤患者化疗前外周血CD4/CD8值与化疗近期疗效的关系。方法应用流式细胞术检测74例NHL患者化疗前外周血CD4/CD8值。结果 CD4/CD8值偏低患者化疗有效率(54.5%)显著低于CD4/CD8值正常或偏高者(90.0%)(P<0.05)。结论 NHL患者免疫功能低下可能影响化疗近期疗效。
目的:分析非霍奇金淋巴瘤患者化療前外週血CD4/CD8值與化療近期療效的關繫。方法應用流式細胞術檢測74例NHL患者化療前外週血CD4/CD8值。結果 CD4/CD8值偏低患者化療有效率(54.5%)顯著低于CD4/CD8值正常或偏高者(90.0%)(P<0.05)。結論 NHL患者免疫功能低下可能影響化療近期療效。
목적:분석비곽기금림파류환자화료전외주혈CD4/CD8치여화료근기료효적관계。방법응용류식세포술검측74례NHL환자화료전외주혈CD4/CD8치。결과 CD4/CD8치편저환자화료유효솔(54.5%)현저저우CD4/CD8치정상혹편고자(90.0%)(P<0.05)。결론 NHL환자면역공능저하가능영향화료근기료효。
Objective To study the relation between CD 4/CD8 in non-Hodgkin ’ s lymphoma ( NHL ) patients before chemotherapy and short-term effect.Methods CD4/CD8 of peripheral blood samples of 74 NHL patients before chemotherapy was determined by flow cytometry .Results Patients with low CD4/CD8 ratios(54.5%) had a significantly lower effective rate than those with normal or high CD4/CD8 ratios(90.0%).Conclusion Low immune functions may undermine short-term effect of chemotherapy in NHL patients .