医学美学美容(中旬刊)
醫學美學美容(中旬刊)
의학미학미용(중순간)
MEDICAL AESTHETICS AND COSMETOLOGY
2014年
7期
17-17
,共1页
激素替代疗法%植物%雌激素类%围绝经期综合征%血脂%副作用
激素替代療法%植物%雌激素類%圍絕經期綜閤徵%血脂%副作用
격소체대요법%식물%자격소류%위절경기종합정%혈지%부작용
hormone replacement therapy%plants%estrogens%perimenopause syndrome%serum lipid%adverse ef ect
目的:探讨绝经前和绝经后患者应用激素替代治疗(HRT)和植物雌激素(PE)治疗对围绝经期综合征的疗效,以期提高围绝经期患者生活质量.方法:采用前瞻性研究,绝经前患者102例,绝经后患者76例.其中HRT组106例、PE组72例.观察患者在用药前、用药3 mo后的围绝经期症状及血脂变化,并观察两种治疗方法的副作用.结果:两组患者的围绝经期症状均有明显减轻,但PE的作用明显次于HRT (P<0.05);HRT组中患者血脂中低密度脂蛋白较用药前明显下降(P<0.05),高密度脂蛋白较用药前明显升高(P<0.05);而PE组中患者血脂波谱无明显改变;治疗过程中所引起的副作用HRT组明显高于PE组(P<0.05).结论:HRT和PE均能明显减轻患者的围绝经期症状,HRT能改善血脂波谱状态,而PE能减少患者因服药带来的副作用.
目的:探討絕經前和絕經後患者應用激素替代治療(HRT)和植物雌激素(PE)治療對圍絕經期綜閤徵的療效,以期提高圍絕經期患者生活質量.方法:採用前瞻性研究,絕經前患者102例,絕經後患者76例.其中HRT組106例、PE組72例.觀察患者在用藥前、用藥3 mo後的圍絕經期癥狀及血脂變化,併觀察兩種治療方法的副作用.結果:兩組患者的圍絕經期癥狀均有明顯減輕,但PE的作用明顯次于HRT (P<0.05);HRT組中患者血脂中低密度脂蛋白較用藥前明顯下降(P<0.05),高密度脂蛋白較用藥前明顯升高(P<0.05);而PE組中患者血脂波譜無明顯改變;治療過程中所引起的副作用HRT組明顯高于PE組(P<0.05).結論:HRT和PE均能明顯減輕患者的圍絕經期癥狀,HRT能改善血脂波譜狀態,而PE能減少患者因服藥帶來的副作用.
목적:탐토절경전화절경후환자응용격소체대치료(HRT)화식물자격소(PE)치료대위절경기종합정적료효,이기제고위절경기환자생활질량.방법:채용전첨성연구,절경전환자102례,절경후환자76례.기중HRT조106례、PE조72례.관찰환자재용약전、용약3 mo후적위절경기증상급혈지변화,병관찰량충치료방법적부작용.결과:량조환자적위절경기증상균유명현감경,단PE적작용명현차우HRT (P<0.05);HRT조중환자혈지중저밀도지단백교용약전명현하강(P<0.05),고밀도지단백교용약전명현승고(P<0.05);이PE조중환자혈지파보무명현개변;치료과정중소인기적부작용HRT조명현고우PE조(P<0.05).결론:HRT화PE균능명현감경환자적위절경기증상,HRT능개선혈지파보상태,이PE능감소환자인복약대래적부작용.
AIM:To compare the treatment ef ects of hormone replacement therapy (HRT)and phytoestrogen (PE)for perimenopausal women.METHODS:Total y 178 patients (102 premenopausal and 76 postmenopausal women)were randomely divided into 2 groups:106 were given HRT and 76 were given PE for 3 months.The side ef ects were compared between the 2 therapies.RESULTS:After 3 months of treatment,perimenopausal symptoms of al patients in the 2 groups were improved,but the improvement in PE group was less obvious than that in HRT group (P<0.05).Lowdensity lipoprotein decreased and highdensity lipoprotein increased in HRT group after treatment (P<0.05 vs PE group);www.zhlzw.com there was no any significant changesinlipoproteinsinPEgroup.SideefectinHRTwasmoresignificantlyseriousthanthatofPEtherapy(P<0.05).CONCLUSION:HRTandPEcanal significantlyimproveperimeno-pausal symptoms,but HRT is bet er in lipoprotein improvement,and PE caused side ef ect is less.