CAJ | 학술논문

目的：探讨老年急性缺血性脑卒中患者下丘脑腺垂体激素水平对预后的影响及相关性。方法收集100例符合诊断标准的急性脑卒中老年患者（≥65岁），用放射免疫法测定皮质醇、促甲状腺激素（TSH）、性激素水平。脑卒中的诊断及分级采用磁共振成像（MRI）＋弥散加权成像（DWI）的结果，脑卒中严重程度与预后用美国国立卫生研究院卒中量表（NIHSS）评分和修订致残量表（mRS）评分。结果皮质醇水平显著增高的患者，其预后越差（P＜0．05），雄激素水平越高的患者其预后越好（P＜0．05），雌激素水平越高的患者其预后越好（P＜0．05），TSH水平越高的患者其预后越差（P＜0．05）。结论下丘脑腺垂体激素水平与老年急性缺血性脑卒中患者预后有显著相关性。
목적：탐토노년급성결혈성뇌졸중환자하구뇌선수체격소수평대예후적영향급상관성。방법수집100례부합진단표준적급성뇌졸중노년환자（≥65세），용방사면역법측정피질순、촉갑상선격소（TSH）、성격소수평。뇌졸중적진단급분급채용자공진성상（MRI）＋미산가권성상（DWI）적결과，뇌졸중엄중정도여예후용미국국립위생연구원졸중량표（NIHSS）평분화수정치잔량표（mRS）평분。결과피질순수평현저증고적환자，기예후월차（P＜0．05），웅격소수평월고적환자기예후월호（P＜0．05），자격소수평월고적환자기예후월호（P＜0．05），TSH수평월고적환자기예후월차（P＜0．05）。결론하구뇌선수체격소수평여노년급성결혈성뇌졸중환자예후유현저상관성。
Objective To investigate the prognosis and correlation analysis between hormonal levels of hy-pothalamus-pituitary and acute senile stroke patient .Methods One hundred stroke patients who aged sixty-five and above were collected in this experiment .The hormonal level of cortisol ,TT3 ,TSH and sex hormone were tested by radioimmunoassay .Diagnosis and classification of stroke were analyzed according to MRI +DWI .The severity of the stroke and prognosis were analyzed according to NIHSS and mRS.Results The prognosis of stroke patients was worse due to high levels of cortisol .But it was better for those with high levels of male hormone ,and female hormone .Conclusion There is a significant correlation between hormonal levels of hypothalamus-pituitary and acute senile stroke patient.