CAJ | 학술논문

目的：观察短暂性脑缺血的不同发作频度对后继脑梗死的影响。方法选取2011～2013年在我院接受治疗的脑梗死患者310例， TIA组患者为脑梗死前同侧发生短暂性脑缺血症状者，剩余患者为非TIA组；其中TIA组65例（在TIA组中按照短暂性脑缺血发作次数的不同分为1次组（8例）、2～3次组（18例）和3次以上组（39例），非TIA组245例。观察不同频度TIA组与非TIA组之间入院后神经功能缺损情况及预后情况。结果在神经功能缺损状况的比较中，TIA组发生中重度神经功能缺损的比例显著小于非TIA组（P<0.05），其中TIA组中2～3次组中轻中重度神经缺损发生的比例均小于其他两组（P<0.05）；在预后上，在Ⅱ级预后中，TIA组所占比例显著高于非TIA组（P<0.05），在TIA组中发作次数为2～3次组在Ⅱ级预后中所占比例显著高于其他两组（P<0.05）。结论短暂性脑缺血的不同发作频度与对应的神经保护性相关。
목적：관찰단잠성뇌결혈적불동발작빈도대후계뇌경사적영향。방법선취2011～2013년재아원접수치료적뇌경사환자310례， TIA조환자위뇌경사전동측발생단잠성뇌결혈증상자，잉여환자위비TIA조；기중TIA조65례（재TIA조중안조단잠성뇌결혈발작차수적불동분위1차조（8례）、2～3차조（18례）화3차이상조（39례），비TIA조245례。관찰불동빈도TIA조여비TIA조지간입원후신경공능결손정황급예후정황。결과재신경공능결손상황적비교중，TIA조발생중중도신경공능결손적비례현저소우비TIA조（P<0.05），기중TIA조중2～3차조중경중중도신경결손발생적비례균소우기타량조（P<0.05）；재예후상，재Ⅱ급예후중，TIA조소점비례현저고우비TIA조（P<0.05），재TIA조중발작차수위2～3차조재Ⅱ급예후중소점비례현저고우기타량조（P<0.05）。결론단잠성뇌결혈적불동발작빈도여대응적신경보호성상관。
Objective To observe the impact of different frequency of transient cerebral ischemia on subsequent cere-bral infarction. Methods A total of 310 patients with cerebral infarction in our hospital from 2011 to 2013 were select-ed as the research objects and divided into TIA group and non-TIA group,the TIA group(65 cases) including cerebral infarction patients with ipsilateral transient cerebral ischemia,which was divided into one time group (8 cases),two to three times group(18 cases) and above three times group(39 cases) according to the attack frequency of transient cere-bral ischemia,and the remaining patients were selected as non-TIA group (245 cases). Neurologic impairment and prognosis of patients in all TIA groups and non-TIA group were compared and observed. Results In the comparison of neurologic impairment,ratio of severe neurologic impairment in TIA was significantly lower than non-TIA group (P<0.05),in TIA group,ratio of moderately severe neurologic impairment in two to three times group was significanly lower than other two groups (P<0.05),and ratio of II level prognosis in TIA group was significantly higher than non-TIA group (P<0.05),in TIA group,ratio of patients with two to three times attack frequency was significantly higher than other two groups (P<0.05). Conclusion Different attack frequency of transient cerebral ischemia has certain relation-ships with neuroprotection.