中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2014年
20期
9-11
,共3页
吕丹%陈众博%邓在春
呂丹%陳衆博%鄧在春
려단%진음박%산재춘
中央型肺癌%液基细胞学%常规涂片%经支气管镜下针吸活检
中央型肺癌%液基細胞學%常規塗片%經支氣管鏡下針吸活檢
중앙형폐암%액기세포학%상규도편%경지기관경하침흡활검
Central lung cancer%Thin prep cytology%Conventional smear%Transbronchial needle aspiration
目的：探讨液基细胞学技术（thin prep cytology test， TCT）在中央型肺癌针吸细胞学诊断中的价值。方法分析127例中央型肺癌患者的经支气管针吸活检（transbronchial needle aspiration， TBNA）标本，随机将患者分为常规涂片（conventional smear， CS）组及CS联合TCT组，其中CS组62例，CS+TCT组65例。比较两组方法的敏感性及特异性。结果 CS 组的敏感性为75.9%，特异性为100.0%；CS+TCT 组的敏感性为96.2%，特异性为100.0%。与CS组相比，CS+TCT组的敏感性明显高于CS组（P=0.000046<0.01）。结论联合使用CS+TCT能提高中央型肺癌针吸细胞学的敏感性，TBNA的TCT检测法可推广应用于临床。
目的：探討液基細胞學技術（thin prep cytology test， TCT）在中央型肺癌針吸細胞學診斷中的價值。方法分析127例中央型肺癌患者的經支氣管針吸活檢（transbronchial needle aspiration， TBNA）標本，隨機將患者分為常規塗片（conventional smear， CS）組及CS聯閤TCT組，其中CS組62例，CS+TCT組65例。比較兩組方法的敏感性及特異性。結果 CS 組的敏感性為75.9%，特異性為100.0%；CS+TCT 組的敏感性為96.2%，特異性為100.0%。與CS組相比，CS+TCT組的敏感性明顯高于CS組（P=0.000046<0.01）。結論聯閤使用CS+TCT能提高中央型肺癌針吸細胞學的敏感性，TBNA的TCT檢測法可推廣應用于臨床。
목적：탐토액기세포학기술（thin prep cytology test， TCT）재중앙형폐암침흡세포학진단중적개치。방법분석127례중앙형폐암환자적경지기관침흡활검（transbronchial needle aspiration， TBNA）표본，수궤장환자분위상규도편（conventional smear， CS）조급CS연합TCT조，기중CS조62례，CS+TCT조65례。비교량조방법적민감성급특이성。결과 CS 조적민감성위75.9%，특이성위100.0%；CS+TCT 조적민감성위96.2%，특이성위100.0%。여CS조상비，CS+TCT조적민감성명현고우CS조（P=0.000046<0.01）。결론연합사용CS+TCT능제고중앙형폐암침흡세포학적민감성，TBNA적TCT검측법가추엄응용우림상。
Objective To explore the diagnostic value of thin prep cytology test(TCT) in central lung cancer. Methods All 127 patients suspected central lung cancer were detected by transbronchial needle aspiration(TBNA). The patients were randomly assigned into two groups, the group of conventional smear,CS (62 cases) and the group of CS+TCT(65 cases). The sensitivity and specificity of two methods were compared. Results The sensitivity and specificity of CS were 75.9%and 100.0% respectively. The sensitivity and specificity of CS+TCT were 96.2% and 100.0% respectively. The sensitivity of CS+TCT was significantly higher than sensitivity of CS in diagnosis of lung cancer (P=0.000046<0.01). Conclusion Combination of CS and TCT techniques can improve the TBNA diagnostic sensitivity of lung cancer. TBNA-TCT detection methods should be applied to clinical activites.
