CAJ | 학술논문

目的：探讨采用美罗培南不同输注方案治疗呼吸机相关肺炎的临床疗效。方法：选取2010年1月至2013年12月入住我院重症医学科的106例呼吸机相关性肺炎的患者为研究对象，将其随机分为对照组和观察组，每组各53例，其中对照组采用间断输注，观察组采用静脉持续输注，后观察两组的临床疗效。结果：观察组在临床疗效上优于对照组，P＜0．05，且该组的机械通气时间比对照组短、经济支出明显小于对照组，两组比较有显著性差异，P＜0．05。结论：采用美罗培南持续输注治疗呼吸机相关肺炎临床疗效较好、可有效减少机械通气时间，同时也减轻了患者的经济负担，是一种安全有效的治疗方式，值得临床采纳。
목적：탐토채용미라배남불동수주방안치료호흡궤상관폐염적림상료효。방법：선취2010년1월지2013년12월입주아원중증의학과적106례호흡궤상관성폐염적환자위연구대상，장기수궤분위대조조화관찰조，매조각53례，기중대조조채용간단수주，관찰조채용정맥지속수주，후관찰량조적림상료효。결과：관찰조재림상료효상우우대조조，P＜0．05，차해조적궤계통기시간비대조조단、경제지출명현소우대조조，량조비교유현저성차이，P＜0．05。결론：채용미라배남지속수주치료호흡궤상관폐염림상료효교호、가유효감소궤계통기시간，동시야감경료환자적경제부담，시일충안전유효적치료방식，치득림상채납。
Objective:To observe the clinical efficacy of different infusion schemes of meropenem in treating ventilator-associated pneumonia .Method:106 cases with ventilator-associated pneumonia treated in our hospital from Jan .2010 to Dec.2013 were selected as research objects and were divided into two groups randomly, the control group and the observation group , each group for 53 cases.The control group received interrupted infusion , and the observation group received continuous venous infusion .The clinical efficacy of two groups was observed .Result: The clinical efficacy of the observation group was better than that of the control group, P<0.05.The duration of ventilatory support of the observation group was shorter than that of the control group , and the economic expense of the observation group was evidently less than that of the con-trol group, which had evident difference , P<0.05.Conclusion: Continuous infusion of meropenem in trea-ting ventilator-associated pneumonia not only has good clinical efficacy and effectively reduces the duration of ventilatory support , but also can reduce the economic burden of the patients , which is an effective treat-ment method and is worthy of application in clinical practice .