中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
14期
2734-2737
,共4页
糖尿病肾病%诊断%Podocalyxin
糖尿病腎病%診斷%Podocalyxin
당뇨병신병%진단%Podocalyxin
Diabetic nephropathies%Diagnosis%Podocalyxin
糖尿病肾病的发病率越来越高,寻求其早期诊断指标十分必要。Podocalyxin作为肾小球足细胞的标记物,近年来成为研究热点。本文将介绍Podocalyxin的生物学结构及生理功能,总结Podocalyxin在糖尿病肾病基础研究及临床观察中的改变及意义,展望检测尿中Podocalyxin的排泄在糖尿病肾病早期诊断的价值。
糖尿病腎病的髮病率越來越高,尋求其早期診斷指標十分必要。Podocalyxin作為腎小毬足細胞的標記物,近年來成為研究熱點。本文將介紹Podocalyxin的生物學結構及生理功能,總結Podocalyxin在糖尿病腎病基礎研究及臨床觀察中的改變及意義,展望檢測尿中Podocalyxin的排洩在糖尿病腎病早期診斷的價值。
당뇨병신병적발병솔월래월고,심구기조기진단지표십분필요。Podocalyxin작위신소구족세포적표기물,근년래성위연구열점。본문장개소Podocalyxin적생물학결구급생리공능,총결Podocalyxin재당뇨병신병기출연구급림상관찰중적개변급의의,전망검측뇨중Podocalyxin적배설재당뇨병신병조기진단적개치。
It is important to search a useful early marker of diabetic nephropathy. Podocalyxin as a marker of podocyte becomes the research focus these years. The features and functions of podocalyxin were reviewed in this paper. Then the basic research and clinical change of podocalyxin in diabetic nephropathy was concluded. And the applications of the increased podocalyxin as an early diagnosis item of diabetic nephropathy in the future were discussed at last.