CAJ | 학술논문

目的探讨原发性干燥综合征(PSS)患者抑郁障碍与生活事件的关系.方法采用抑郁自评量表(SDS)及生活事件量表(LES),对80名诊断为抑郁障碍的PSS患者(研究组)抑郁状态及生活事件进行评定,同时按照研究组的年龄、性别构成,选取80名排除合并抑郁障碍的PSS患者(对照组)进行对照,并对研究组的生活事件及抑郁状态进行相关分析.结果研究组患者经历的生活事件总值、负性生活事件值、SDS评分及生活事件频率[分别为(32.72±13.93)分,(24.36±11.24)分,(58.60±16.78)分,91.3％]均高于对照组[分别为(26.96±11.62)分,(15.88±9.97)分,(39.34±14.69)分,40％],差异具有统计学意义(P＜0.05),正性生活事件值[(7.15±5.84)分]低于对照组[(9.76±7.29)分],差异具有统计学意义(P＜0.05),负性生活事件主要表现在家庭生活及工作学习方面；相关分析发现,研究组的负性生活事件值及生活事件总值与抑郁程度均呈显著正相关(P＜0.01),而正性生活事件值与抑郁程度则呈负相关(P＜0.05).结论 PSS合并抑郁障碍患者经历更多的负性生活事件,负性生活事件在其抑郁障碍的发病过程中起着重要作用.
목적 탐토원발성간조종합정(PSS)환자억욱장애여생활사건적관계.방법 채용억욱자평량표(SDS)급생활사건량표(LES),대80명진단위억욱장애적PSS환자(연구조)억욱상태급생활사건진행평정,동시안조연구조적년령、성별구성,선취80명배제합병억욱장애적PSS환자(대조조)진행대조,병대연구조적생활사건급억욱상태진행상관분석.결과 연구조환자경력적생활사건총치、부성생활사건치、SDS평분급생활사건빈솔[분별위(32.72±13.93)분,(24.36±11.24)분,(58.60±16.78)분,91.3％]균고우대조조[분별위(26.96±11.62)분,(15.88±9.97)분,(39.34±14.69)분,40％],차이구유통계학의의(P＜0.05),정성생활사건치[(7.15±5.84)분]저우대조조[(9.76±7.29)분],차이구유통계학의의(P＜0.05),부성생활사건주요표현재가정생활급공작학습방면；상관분석발현,연구조적부성생활사건치급생활사건총치여억욱정도균정현저정상관(P＜0.01),이정성생활사건치여억욱정도칙정부상관(P＜0.05).결론 PSS합병억욱장애환자경력경다적부성생활사건,부성생활사건재기억욱장애적발병과정중기착중요작용.
Objective To explore the relationship between life events and depression of patients with primary sjgren's syndrome (PSS).Methods 80 patients with PSS complicating depressive disorder were tested by self-rating depression scale(SDS) and life event scale (LES),and compared with the control group including 80 PSS patients with non-depressive disorder matched with age and sex.Then the correlation between SDS and LES were analyzed.Results The total score of life events (32.72 ± 13.93),the score of negative life events (24.36 ±11.24),the score of SDS(58.60 ± 16.78) and the frequency of life events(91.3％) in the research group were higher than those in control group(P ＜ 0.05),but the positive life events score (7.15 ± 5.84) was lower than that in control group (9.76 ± 7.29),and there was statistically significant difference between the two groups (P ＜ 0.05),there were more negative life events,especially on the aspects of family,work and study in the research group.There was positive correlation among the negative life events score,total score of life events and SDS score in the research group(P＜ 0.01),meanwhile,negative correlation was revealed between the score of positive life events and SDS score in the research group(P ＜ 0.05).Conclusion Patients with PSS complicating depressive disorder experienced more negative life events which play an important role in depression of patients with PSS.