CAJ | 학술논문

目的：探讨血清降钙素原监测在判断重症患者是否并发感染的的价值。方法收集重症监护病房（ICU）188例患者分为感染组和未感染组，同时监测血清 PCT、CRP、白细胞总数和中性粒细胞比值；感染组中41例患者连续1～6 d 动态测定 PCT及相关指标，并进行统计学分析。结果重症感染组（112例）和重症非感染组（76例）的年龄、PCT、CRP 比较差异有统计学意义；除感染组 PCT 和 CRP 相关性比较有统计学意义外，其他指标比较差异无统计学意义（P ＞0．05）；感染者中出院组（32例）和死亡组（9例），第1、2天两者 PCT 值比较 P ＞0．05，第3～6天 PCT 值比较，差异有统计学意义（P ＜0．05）。结论血清 PCT 是判断重症患者感染与否的有效指标，独立并且明显优于传统的炎症指标，在重症患者中动态监测其水平对判断感染的控制情况具有一定价值。
목적：탐토혈청강개소원감측재판단중증환자시부병발감염적적개치。방법수집중증감호병방（ICU）188례환자분위감염조화미감염조，동시감측혈청 PCT、CRP、백세포총수화중성립세포비치；감염조중41례환자련속1～6 d 동태측정 PCT급상관지표，병진행통계학분석。결과중증감염조（112례）화중증비감염조（76례）적년령、PCT、CRP 비교차이유통계학의의；제감염조 PCT 화 CRP 상관성비교유통계학의의외，기타지표비교차이무통계학의의（P ＞0．05）；감염자중출원조（32례）화사망조（9례），제1、2천량자 PCT 치비교 P ＞0．05，제3～6천 PCT 치비교，차이유통계학의의（P ＜0．05）。결론혈청 PCT 시판단중증환자감염여부적유효지표，독립병차명현우우전통적염증지표，재중증환자중동태감측기수평대판단감염적공제정황구유일정개치。
Objective To explore the value of serum procalcitonin detection in judging whether severe patients complicate with infection.Methods 188 patients in the intensive care unit (ICU)were collected and divided into the infection and non-infection groups.The serum procalcitonin(PCT),C-reactive protein(CRP),total number of white blood cells(WBC)and neutrophile cell ratio were simultaneously monitored;41 cases in the infection group dynamically monitored PCT and related indicators for continuous 1-6 d and the statistical analysis was conducted.Results The age,PCT and CRP had statistically significant differences between the infection group(112 cases)and non-infection group(76 cases).Except the correlation of PCT and CRP in the infection group showing statistical significance,the comparison of the other indicators had no statistical differences.In the infectors,the PCT value comparison between on 1 d and 2 d in the hospital discharge group(32 cases)and the death group (9 cases)showed P >0.05,the PCT value comparison between on 3-6 d showed P <0.05.Conclusion Serum PCT is an effective indicator to judge whether se-vere infected patient has infection and is significantly superior to the traditional inflammatory indicators.Dynamically monitoring the PCT level in the critical patients has a certain value to judge the control situation of infection.