CAJ | 학술논문

目的：分析醒脑静注射液联合纳洛酮注射液治疗急性重度酒精中毒的疗效。方法：选择2012年2月～2013年10月我院确诊的78例急性重度酒精中毒患者随机分为2组，每组39例，对照组进行常规洗胃，给予速尿及维生素静脉滴注等常规治疗基础上，纳洛酮0.4mg静脉推注，随后将0.8～1.2mg纳洛酮溶于5％葡萄糖溶液250ml中静脉滴注；治疗组在对照组的基础上，给予醒脑静注射液20ml溶于5％葡萄糖注射液250ml中静脉滴注，观察两组患者的显效和症状消失时间，并比较两组患者的意识清醒、能正确回答问题以及能够独立行走的时间。结果：治疗组患者的显效时间和症状消失时间均短于对照组(P﹤0.05)；治疗组患者的意识清醒时间、能正确回答问题时间以及能够独立行走时间也均短于对照组，其差异均有统计学意义(P﹤0.05)。结论：醒脑静联合纳洛酮治疗急性重度酒精中毒疗效显著，其清醒时间明显缩短，值得在临床推广应用。
목적：분석성뇌정주사액연합납락동주사액치료급성중도주정중독적료효。방법：선택2012년2월～2013년10월아원학진적78례급성중도주정중독환자수궤분위2조，매조39례，대조조진행상규세위，급여속뇨급유생소정맥적주등상규치료기출상，납락동0.4mg정맥추주，수후장0.8～1.2mg납락동용우5％포도당용액250ml중정맥적주；치료조재대조조적기출상，급여성뇌정주사액20ml용우5％포도당주사액250ml중정맥적주，관찰량조환자적현효화증상소실시간，병비교량조환자적의식청성、능정학회답문제이급능구독립행주적시간。결과：치료조환자적현효시간화증상소실시간균단우대조조(P﹤0.05)；치료조환자적의식청성시간、능정학회답문제시간이급능구독립행주시간야균단우대조조，기차이균유통계학의의(P﹤0.05)。결론：성뇌정연합납락동치료급성중도주정중독료효현저，기청성시간명현축단，치득재림상추엄응용。
Objective:To analyze the curative effect of Xingnaojing injection combined with naloxone injection in the treatment of acute severe alcoholism. Methods 78 cases of acute severe alcoholism in our hospital from 2012 February to 2013 October were randomly divided into 2 groups, 39 cases in each group, the control group were given routine gastric lavage, conventional therapy and intravenous infusion of furosemide vitamins such as 0.4mg, naloxone intravenous injection, then 0.8~1.2mg naloxone dissolved in 5%glucose solution 250ml intravenous injection;the patients in the treatment group were given the treatment on the basis of Xingnaojing injection, and 20ml dissolved in 5% Glucose Injection 250ml intravenous injection.The effect and symptoms disappeared time, the duration of answering questions and walking independently were compared. Results: The duration of effective time and the symptoms disappeared time of the treatment group were shorter than that of the control group (P<0.05); The conscious time and the duration of answering the question correctly and walking independently of the treatment group was shorter than that of the control group,and the differences were statistically significant (P<0.05). Conclusion Xingnaojing combined with naloxone in treatment of acute severe alcoholism effect is significant, the recovery time is obviously shorter and it is worthy of promotion in clinical application.