CAJ | 학술논문

目的：观察和分析头孢菌素类药物皮肤过敏的实验以及皮试方法。方法选择我院2010年1月至2011年1月接收的治疗过程中使用头孢菌素类药物的500例住院患者，随机平均分成皮试组与非皮试组，分别观察患者用药后的情况。结果有青霉素过敏史的患者占19.80%，皮试阳性占有率中，其他物质过敏史的占12.02%，无过敏史的占0.55%；皮试阴性组用药后发生的不良用药反应以及过敏反应明显低于非皮试组患者，两组数据差异显著，具有统计学意义。结论影响头孢菌素类药物出现不良药物反应以及皮试阳性发生率的主要因素是患者的过敏史，因此，对具有过敏史患者用药前应该对患者进行采取拟用药皮试。
목적：관찰화분석두포균소류약물피부과민적실험이급피시방법。방법선택아원2010년1월지2011년1월접수적치료과정중사용두포균소류약물적500례주원환자，수궤평균분성피시조여비피시조，분별관찰환자용약후적정황。결과유청매소과민사적환자점19.80%，피시양성점유솔중，기타물질과민사적점12.02%，무과민사적점0.55%；피시음성조용약후발생적불량용약반응이급과민반응명현저우비피시조환자，량조수거차이현저，구유통계학의의。결론영향두포균소류약물출현불량약물반응이급피시양성발생솔적주요인소시환자적과민사，인차，대구유과민사환자용약전응해대환자진행채취의용약피시。
ObjectiveTo observe the method and experimental analysis of cephalosporins allergic skin and skin test.MethodsThe use of cephalosporins in the treatment in our hospital from January 2010 to January 2011 received in 500 patients, were randomly divided into test group and non skin test group, patients were observed after treatment of the situation.ResultsA history of penicillin allergy skin test positive patients accounted for 19.80%, share, other allergy history accounted for 12.02%, non allergic history accounted for 0.55%; adverse drug reaction of skin test negative groups after medication and allergy skin test group was obviously lower than that in patients with signiifcant difference, two groups of data, with statistical signiifcance.ConclusionThe effect of cephalosporins adverse drug reactions as well as the main factors of skin test positive rate in patients with a history of allergy, therefore, to have drug allergy history patients before patients should be on the take a skin test to use.