重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2014年
20期
2569-2571
,共3页
张萍%邓勇%樊海宁%王海久%乜国雁%王花%张朝霞%刘芳
張萍%鄧勇%樊海寧%王海久%乜國雁%王花%張朝霞%劉芳
장평%산용%번해저%왕해구%먀국안%왕화%장조하%류방
包虫病/棘球蚴病%组合抗原金标渗滤诊断法%影像学诊断
包蟲病/棘毬蚴病%組閤抗原金標滲濾診斷法%影像學診斷
포충병/극구유병%조합항원금표삼려진단법%영상학진단
hydatidosis/echinococcosis%multiple antigens dot immunogold filtration assay%imaging diagnosis
目的:对比研究组合抗原金标渗滤(DIGFA )法与影像学对两型包虫病的诊断价值。方法对病理检查确诊的包虫病患者167例,分别行DIGFA诊断(DIGFA组)和影像学诊断(影像学组),然后进行对比研究。结果囊型包虫病(CE)中DIG-FA组确诊率为74.60%,影像学组确诊率为90.48%(P<0.01);泡型包虫病(AE)中DIGFA组确诊率为92.68%,影像学组确诊率为73.17%(P<0.05)。在包囊小于5 cm时,DIGFA 组AE和CE的检出率分别为91.67%和61.11%(P<0.05),在包囊为5~<10 cm 时,DIGFA 组 AE和CE的检出率分别为94.12%和71.43%(P<0.05);DIGFA 组 CE在包囊大于或等于10 cm、<5 cm和5~<10 cm的检出率为94.12%、61.11%和71.43%(P<0.05);DIGFA组 AE和CE总确诊率分别为92.68%,74.60%(P<0.05)。结论影像学对CE确诊率高;DIGFA对AE确诊率高,特别是对AE早期诊断更加有临床意义。在影像学诊断的基础上,辅以DIGFA有益于准确判断两型包虫病。
目的:對比研究組閤抗原金標滲濾(DIGFA )法與影像學對兩型包蟲病的診斷價值。方法對病理檢查確診的包蟲病患者167例,分彆行DIGFA診斷(DIGFA組)和影像學診斷(影像學組),然後進行對比研究。結果囊型包蟲病(CE)中DIG-FA組確診率為74.60%,影像學組確診率為90.48%(P<0.01);泡型包蟲病(AE)中DIGFA組確診率為92.68%,影像學組確診率為73.17%(P<0.05)。在包囊小于5 cm時,DIGFA 組AE和CE的檢齣率分彆為91.67%和61.11%(P<0.05),在包囊為5~<10 cm 時,DIGFA 組 AE和CE的檢齣率分彆為94.12%和71.43%(P<0.05);DIGFA 組 CE在包囊大于或等于10 cm、<5 cm和5~<10 cm的檢齣率為94.12%、61.11%和71.43%(P<0.05);DIGFA組 AE和CE總確診率分彆為92.68%,74.60%(P<0.05)。結論影像學對CE確診率高;DIGFA對AE確診率高,特彆是對AE早期診斷更加有臨床意義。在影像學診斷的基礎上,輔以DIGFA有益于準確判斷兩型包蟲病。
목적:대비연구조합항원금표삼려(DIGFA )법여영상학대량형포충병적진단개치。방법대병리검사학진적포충병환자167례,분별행DIGFA진단(DIGFA조)화영상학진단(영상학조),연후진행대비연구。결과낭형포충병(CE)중DIG-FA조학진솔위74.60%,영상학조학진솔위90.48%(P<0.01);포형포충병(AE)중DIGFA조학진솔위92.68%,영상학조학진솔위73.17%(P<0.05)。재포낭소우5 cm시,DIGFA 조AE화CE적검출솔분별위91.67%화61.11%(P<0.05),재포낭위5~<10 cm 시,DIGFA 조 AE화CE적검출솔분별위94.12%화71.43%(P<0.05);DIGFA 조 CE재포낭대우혹등우10 cm、<5 cm화5~<10 cm적검출솔위94.12%、61.11%화71.43%(P<0.05);DIGFA조 AE화CE총학진솔분별위92.68%,74.60%(P<0.05)。결론영상학대CE학진솔고;DIGFA대AE학진솔고,특별시대AE조기진단경가유림상의의。재영상학진단적기출상,보이DIGFA유익우준학판단량형포충병。
Objective To compare and study the value of multiple antigens dot immunogold filtration assay (DIGFA ) and ima-ging diagnosis for rapid diagnosis of two kinds of echinococcosises .Methods 167 cases of hydatid patients diagnosied by pathologi-cal examination were divided into the DIGFA group for diagnosis of DIGFA and the control group for imaging diagnosis .Results The diagnosis rate of cystic echinococcosis (CE) in the DIGFA group was 74 .60% and control group was 90 .48% (P<0 .01);the diagnosis of alveolar echinococcosis(AE) in the DIGFA group was 92 .68% and the control group was 73 .17% (P<0 .05);when the cystica<5 cm ,the diagnosis rate of AE and CE in the DIGFA group was 91 .67% and 61 .11% (P<0 .05) ,when the cystica 5- <10 cm ,the detection rate of AE and CE in the DIGFA group was 94 .12% and 71 .43% (P<0 .05) .When the cystica≥10 cm ,<5 cm or between 5 - < 10 cm ,the detection rate of CE in DIGFA group was 94 .12% ,61 .11% ,71 .43 ,respectively (P<0 .05);The totle detection rates of the AE and CE in DIGFA group were 92 .68% and 74 .60% (P<0 .05) .Conclusion Imaging di-agnosis for the CE was higher and the DIGFA diagnosis for the AE was higher and the DIGFA also had clinical significance espe-cially applicated to the early diagnosis of AE .With the help of the imaging diagnosis ,the DIGFA could diagnose two kinds of echi-nococcosises correctly and it provided the benefits of specificity and sensitivity and performed easily .