重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2014年
20期
2563-2564,2568
,共3页
磁共振成像%血脂%危险因素%腔隙性脑梗死
磁共振成像%血脂%危險因素%腔隙性腦梗死
자공진성상%혈지%위험인소%강극성뇌경사
magnetic resonance imaging%blood lipids%risk factors%lacunar infarction
目的:探讨腔隙性脑梗死(LI)的MRI表现与血脂变化的相关性。方法回顾性分析68例LI患者的MRI表现及其血脂水平,选取62例同期住院就诊的非心脑血管疾病患者为对照组,应用多元Logistic回归分析LI的M RI表现与血脂变化的相关关系。结果 L I患者M RI共检出299个腔隙性病灶,其中梗死病灶位于左侧大脑半球58个(19.40%),右侧大脑半球26个(8.70%),双侧基底节区73个(24.41%),丘脑27个(9.03%),侧脑室旁放射冠54个(18.06%),脑干39个(13.04%),小脑22个(7.36%)。LI患者的TC、TG、LDL-C和Ox-LDL水平显著增高(P<0.05),而HDL-C的水平明显低于对照组(P<0.05)。多元Logistic回归分析显示TC、TG、LDL-C、HDL-C和Ox-LDL对LI的相对危险度分别为1.56、1.27、1.39、1.46和1.44。结论 LI患者的M RI表现与血脂水平有一定程度的相关性,血脂水平升高可能是L I的重要危险因素。
目的:探討腔隙性腦梗死(LI)的MRI錶現與血脂變化的相關性。方法迴顧性分析68例LI患者的MRI錶現及其血脂水平,選取62例同期住院就診的非心腦血管疾病患者為對照組,應用多元Logistic迴歸分析LI的M RI錶現與血脂變化的相關關繫。結果 L I患者M RI共檢齣299箇腔隙性病竈,其中梗死病竈位于左側大腦半毬58箇(19.40%),右側大腦半毬26箇(8.70%),雙側基底節區73箇(24.41%),丘腦27箇(9.03%),側腦室徬放射冠54箇(18.06%),腦榦39箇(13.04%),小腦22箇(7.36%)。LI患者的TC、TG、LDL-C和Ox-LDL水平顯著增高(P<0.05),而HDL-C的水平明顯低于對照組(P<0.05)。多元Logistic迴歸分析顯示TC、TG、LDL-C、HDL-C和Ox-LDL對LI的相對危險度分彆為1.56、1.27、1.39、1.46和1.44。結論 LI患者的M RI錶現與血脂水平有一定程度的相關性,血脂水平升高可能是L I的重要危險因素。
목적:탐토강극성뇌경사(LI)적MRI표현여혈지변화적상관성。방법회고성분석68례LI환자적MRI표현급기혈지수평,선취62례동기주원취진적비심뇌혈관질병환자위대조조,응용다원Logistic회귀분석LI적M RI표현여혈지변화적상관관계。결과 L I환자M RI공검출299개강극성병조,기중경사병조위우좌측대뇌반구58개(19.40%),우측대뇌반구26개(8.70%),쌍측기저절구73개(24.41%),구뇌27개(9.03%),측뇌실방방사관54개(18.06%),뇌간39개(13.04%),소뇌22개(7.36%)。LI환자적TC、TG、LDL-C화Ox-LDL수평현저증고(P<0.05),이HDL-C적수평명현저우대조조(P<0.05)。다원Logistic회귀분석현시TC、TG、LDL-C、HDL-C화Ox-LDL대LI적상대위험도분별위1.56、1.27、1.39、1.46화1.44。결론 LI환자적M RI표현여혈지수평유일정정도적상관성,혈지수평승고가능시L I적중요위험인소。
Objective To explore relationship between magnetic resonance imaging (MRI) performance and lipid levels in pa-tients with lacunar infarction (LI) .Methods 68 patients with LI were retrospectively analyzed ,62 cases patients without heart ce-rebrovascular disease in the same period were choosen as control group ,the multivariate logistic regression was used to analyze the relationship between MRI performance ,the changed level of lipid .Results A total of 299 lacunar lesions were detected by MRI ,in which there were 58(19 .40% )in the left cerebral hemisphere ,26(8 .70% ) in the right hemisphere ,73(24 .41% ) in the bilateral basal ganglia ,27 (9 .03% ) in thalamus ,54 (18 .06% ) in the lateral ventricles corona radiata ,39 (13 .04% ) in brainstem ,and 22 (7 .36% ) in cerebellum .TC ,TG ,LDL-C and Ox-LDL levels in LI patients were significantly higher than the controls (P<0 .05) , while HDL-C levels were significantly lower than the controls (P<0 .05) .Multivariate Logistic regression analysis showed that relative risk of TC ,TG ,LDL-C ,HDL-C and Ox-LDL to LI were 1 .56 ,1 .27 ,1 .39 ,1 .46 and 1 .44 .Conclusion The MRI manifestations and lipid levels of LI have a certain degree of correlation ,and elevated blood lipid levels may be important risk factors for LI .