中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
21期
5-7
,共3页
胸腹水%可溶性CD44v6%腺苷脱氨酶%干扰素-γ
胸腹水%可溶性CD44v6%腺苷脫氨酶%榦擾素-γ
흉복수%가용성CD44v6%선감탈안매%간우소-γ
Pleuroperitoneal effusions%Soluble CD44v6%Adenosine deaminase%Interferon-γ
目的：探讨可溶性CD44v6(sCD44v6)、腺苷脱氨酶(ADA)、干扰素-γ(IFN-γ)联合检测对良、恶性胸腹水的鉴别诊断价值。方法取结核性胸腹水28例(结核组)、恶性胸腹水32例(恶性组)、炎性胸腹水20例(炎性组)，分别用酶联免疫吸附试验(ELISA)及化学法检测胸、腹水sCD44v6、ADA、IFN-γ水平。结果恶性组sCD44v6水平明显高于结核组及炎性组；结核组ADA、IFN-γ水平明显高于恶性组及炎性组，差异有统计学意义(P<0.05)。sCD44v6诊断恶性胸腹水的阳性率为87.5%；ADA诊断结核性胸腹水的阳性率为89.2%；IFN-γ在诊断结核性胸腹水时阳性率为96.4%。结论sCD44v6、ADA、IFN-γ联合测定对于良恶性胸腹水的鉴别诊断有重要价值。
目的：探討可溶性CD44v6(sCD44v6)、腺苷脫氨酶(ADA)、榦擾素-γ(IFN-γ)聯閤檢測對良、噁性胸腹水的鑒彆診斷價值。方法取結覈性胸腹水28例(結覈組)、噁性胸腹水32例(噁性組)、炎性胸腹水20例(炎性組)，分彆用酶聯免疫吸附試驗(ELISA)及化學法檢測胸、腹水sCD44v6、ADA、IFN-γ水平。結果噁性組sCD44v6水平明顯高于結覈組及炎性組；結覈組ADA、IFN-γ水平明顯高于噁性組及炎性組，差異有統計學意義(P<0.05)。sCD44v6診斷噁性胸腹水的暘性率為87.5%；ADA診斷結覈性胸腹水的暘性率為89.2%；IFN-γ在診斷結覈性胸腹水時暘性率為96.4%。結論sCD44v6、ADA、IFN-γ聯閤測定對于良噁性胸腹水的鑒彆診斷有重要價值。
목적：탐토가용성CD44v6(sCD44v6)、선감탈안매(ADA)、간우소-γ(IFN-γ)연합검측대량、악성흉복수적감별진단개치。방법취결핵성흉복수28례(결핵조)、악성흉복수32례(악성조)、염성흉복수20례(염성조)，분별용매련면역흡부시험(ELISA)급화학법검측흉、복수sCD44v6、ADA、IFN-γ수평。결과악성조sCD44v6수평명현고우결핵조급염성조；결핵조ADA、IFN-γ수평명현고우악성조급염성조，차이유통계학의의(P<0.05)。sCD44v6진단악성흉복수적양성솔위87.5%；ADA진단결핵성흉복수적양성솔위89.2%；IFN-γ재진단결핵성흉복수시양성솔위96.4%。결론sCD44v6、ADA、IFN-γ연합측정대우량악성흉복수적감별진단유중요개치。
Objective To investigate the value of combined detection of soluble CD44v6(sCD44v6),adenosine deaminase(ADA) and interferon-γ(IFN-γ) in differentiating malignant from benign pleuroperitoneal effusions.Methods Chose 28 cases of tuberculous pleuroperitoneal effusions(tuberculous group), 32 cases of malignant pleuroperitoneal effusions(malignant group), 20 cases of inflammatory pleuroperitoneal effusions(inflammatory group), sCD44v6, ADA, IFN-γlevel were detected respectively by enzyme-linked immunosorbent assay(ELISA) and chemical method.Results sCD44v6 level in malignant pleuroperitoneal effusions group was significantly higher than that in tuberculous and inflammatory pleuroperitoneal effusions group; the levels of ADA and IFN-γin tuberculous pleuroperitoneal effusions group was significantly higher in malignant and inflammatory pleuroperitoneal effusions group, the difference was statistically significant(P<0.05). The positive rate of sCD44v6 diagnosis of malignant pleural effusion was 87.5%; the positive rate of ADA in the diagnosis of tuberculous pleural effusion was 89.2%; IFN-gamma in the diagnosis of tuberculous pleuroperitoneal effusion, the positive rate was 96.4%.Conclusion CD44v6, ADA, IFN-γcombined detection has important value in differentiating malignant from benign pleuroperitoneal effusions.
