CAJ | 학술논문

目的：探讨连续性肾替代疗法治疗危重症感染患者的作用及效果。方法回顾性分析郑州市第一人民医院2011年1月~2013年8月收治的100例危重症患者的临床资料，所有患者均给予连续性肾替代疗法治疗，观察和分析治疗前后急性病生理学、长期健康评价(APACHE)II评分、血气指标、血常规、电解质(血钠、血钾)和肾功能(尿素、肌酐、尿酸)的变化。结果连续性肾替代疗法治疗后，88例患者的体温均有一定程度的下降，呼吸困难症状明显减轻。64例患者成功救治，36例混合感染患者死亡。连续性肾替代疗法治疗后患者的血气分析和血常规各项指标均较治疗前显著改善，差异均有统计学意义(P<0.05)；治疗后的APACHEII评分、电解质、肾功能均较治疗前明显改善。结论连续性肾替代疗法治疗危重症感染具有良好的效果，可有效改善患者的A-PACHEII评分、电解质及肾功能，是一种有效的辅助治疗措施。
목적：탐토련속성신체대요법치료위중증감염환자적작용급효과。방법회고성분석정주시제일인민의원2011년1월~2013년8월수치적100례위중증환자적림상자료，소유환자균급여련속성신체대요법치료，관찰화분석치료전후급성병생이학、장기건강평개(APACHE)II평분、혈기지표、혈상규、전해질(혈납、혈갑)화신공능(뇨소、기항、뇨산)적변화。결과련속성신체대요법치료후，88례환자적체온균유일정정도적하강，호흡곤난증상명현감경。64례환자성공구치，36례혼합감염환자사망。련속성신체대요법치료후환자적혈기분석화혈상규각항지표균교치료전현저개선，차이균유통계학의의(P<0.05)；치료후적APACHEII평분、전해질、신공능균교치료전명현개선。결론련속성신체대요법치료위중증감염구유량호적효과，가유효개선환자적A-PACHEII평분、전해질급신공능，시일충유효적보조치료조시。
Objective To analyze the role and efficacy of continuous renal replacement therapy for patients with criti-cally ill infected. Methods The clinical data of 100 cases of critically ill infected patients who had been treated by continuous renal replacement therapy in the First People's Hospital of Zhengzhou City from January 2011 to August 2013 were retrospective analyzed. The change of APACHEII score, physiology of acute disease, blood gas, blood rou-tine examination, serum electrolytes (sodium, potassium ), renal function (BUN, creatinine, uric acid) were observed and compared. Results Temperature of 88 patients were decreased in a certain degree, breathing difficulty were relieved significantly after continuous renal replacement therapy. 64 cases were successful treated, 18 cases died because of mixed infections. The blood indicators and all blood parameters were significantly improved after continuous renal re-placement therapy, the differences were statistically significant (P<0.05). The APACHEII score, blood indicators, all blood parameters, and Serum electrolytes, renal function were improved after continuous renal replacement therapy. Conclusion The effects of continuous renal replacement therapy is satisfactory for patients with critically ill infected, which can improve the APACHEII score, serum electrolytes, and renal function effectivity, it is an effective adjuvant treatment.