CAJ | 학술논문

目的：探究与分析非洛地平联合倍他洛克治疗34例高血压临床效果分析。方法高血压患者34例，将其作为临床研究对象，对其采用非洛地平联合倍他洛克治疗，观察该组患者治疗前后血压及生理指标变化情况。结果该组患者在治疗1周后较治疗前相比，收缩压及舒张压有了明显下降，治疗6~12周血压下降更加显著(P<0.05)；该组患者治疗前后血清总胆固醇(TC)、甘油三酯(TG)、血尿素氮(BUN)、血肌酐(CR)指标差异无统计学意义(P>0.05)；该组患者治疗后较治疗前相比，血尿酸(UA)和白蛋白(Alb)有了明显下降(P<0.05)。该组患者共34例中出现3例面红(8.82%)、4例心悸(11.76%)、3例头痛(8.82%)、3例头晕(8.82%)，因症状较轻，未采取停药处理，数天后症状自行消失。结论对于高血压患者采用非洛地平联合倍他洛克治疗后的临床效果较为显著，能够有效降低患者血压，且在治疗过程中未出现不良反应，具有一定的安全性。
목적：탐구여분석비락지평연합배타락극치료34례고혈압림상효과분석。방법고혈압환자34례，장기작위림상연구대상，대기채용비락지평연합배타락극치료，관찰해조환자치료전후혈압급생리지표변화정황。결과해조환자재치료1주후교치료전상비，수축압급서장압유료명현하강，치료6~12주혈압하강경가현저(P<0.05)；해조환자치료전후혈청총담고순(TC)、감유삼지(TG)、혈뇨소담(BUN)、혈기항(CR)지표차이무통계학의의(P>0.05)；해조환자치료후교치료전상비，혈뇨산(UA)화백단백(Alb)유료명현하강(P<0.05)。해조환자공34례중출현3례면홍(8.82%)、4례심계(11.76%)、3례두통(8.82%)、3례두훈(8.82%)，인증상교경，미채취정약처리，수천후증상자행소실。결론대우고혈압환자채용비락지평연합배타락극치료후적림상효과교위현저，능구유효강저환자혈압，차재치료과정중미출현불량반응，구유일정적안전성。
Objective To explore and analyze the combination of felodipine and metoprolol on the clinical effect of treatment of 34 cases of hypertension. Methods Selected 34 cases of hypertensive patients as the research object, treated with combination of felodipine and metoprolol treatment, observed the change of blood pressure and physiological index before and after the treatment. Results Systolic and diastolic blood pressure decreased obviously, after 6~12 weeks, the blood pressure decreased significantly(P<0.05);TC, TG, BUN, CR showed no significant difference before and after treatment(P>0.05);UA and Alb in urine was decreased obviously after treatment(P<0.05). The group of 3 patients with a total of 34 cases of red appeared (8.82%), 4 cases(11.76%) of palpitation, 3 cases(8.82%) of headache, 3 cases(8.82%) of dizziness, because the symptom was lighter, without taking the withdrawal treatment, several days later the symptoms disappeared. Conclusion Clinical effect of combination of felodipine and metoprolol in treatment of hypertensive patients is significant, which can effectively reduce the blood pressure safely with no adverse reaction in the treatment process.