中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
22期
51-52
,共2页
利多卡因%静脉注射%表面麻醉%插管反应
利多卡因%靜脈註射%錶麵痳醉%插管反應
리다잡인%정맥주사%표면마취%삽관반응
Lidocaine%Intravenous injection%Surface anesthesia%Intubation reaction
目的：观察不同方法应用利多卡因预防气管插管反应的有效性实用性。方法：选择 ASAⅠ～Ⅱ级患者45例，年龄18～60岁，随机分为3组，A组无表面麻醉、无静脉注射利多卡因，B组2%利多卡因3 ml咽喉部气管内表面麻醉，C组2%利多卡因1 mg/kg静脉注射。记录麻醉诱导前、气管插管前(即准备行气管插管时)以及气管插管后1min血压、心率的变化以及呛咳反应的情况。结果：3组患者气管插管前SBP、DBP、HR均明显下降(P＜0.001)，3组间比较差异无统计学意义(P＞0.05)；A组在气管插管后1 min较麻醉诱导前及气管插管前SBP、DBP、HR明显增加，差异有统计学意义(P＜0.01)，气管插管时出现呛咳反应8例。B组患者气管插管后1分钟较气管插管前SBP、DBP、HR明显增加，差异有统计学意义(P＜0.001)，较诱导前差异无统计学意义(P＞0.05)，气管插管时出现呛咳反应2例。C组患者气管插管反应不大，气管插管后1 min较气管插管前SBP、DBP、HR无明显变化，差异无统计学意义(P＞0.05)，气管插管时没有出现呛咳反应。结论：利多卡因静脉注射与表面麻醉均能预防气管插管反应，但静脉注射较表面麻醉更能有效预防气管插管反应，且给药方便实用性强。
目的：觀察不同方法應用利多卡因預防氣管插管反應的有效性實用性。方法：選擇 ASAⅠ～Ⅱ級患者45例，年齡18～60歲，隨機分為3組，A組無錶麵痳醉、無靜脈註射利多卡因，B組2%利多卡因3 ml嚥喉部氣管內錶麵痳醉，C組2%利多卡因1 mg/kg靜脈註射。記錄痳醉誘導前、氣管插管前(即準備行氣管插管時)以及氣管插管後1min血壓、心率的變化以及嗆咳反應的情況。結果：3組患者氣管插管前SBP、DBP、HR均明顯下降(P＜0.001)，3組間比較差異無統計學意義(P＞0.05)；A組在氣管插管後1 min較痳醉誘導前及氣管插管前SBP、DBP、HR明顯增加，差異有統計學意義(P＜0.01)，氣管插管時齣現嗆咳反應8例。B組患者氣管插管後1分鐘較氣管插管前SBP、DBP、HR明顯增加，差異有統計學意義(P＜0.001)，較誘導前差異無統計學意義(P＞0.05)，氣管插管時齣現嗆咳反應2例。C組患者氣管插管反應不大，氣管插管後1 min較氣管插管前SBP、DBP、HR無明顯變化，差異無統計學意義(P＞0.05)，氣管插管時沒有齣現嗆咳反應。結論：利多卡因靜脈註射與錶麵痳醉均能預防氣管插管反應，但靜脈註射較錶麵痳醉更能有效預防氣管插管反應，且給藥方便實用性彊。
목적：관찰불동방법응용리다잡인예방기관삽관반응적유효성실용성。방법：선택 ASAⅠ～Ⅱ급환자45례，년령18～60세，수궤분위3조，A조무표면마취、무정맥주사리다잡인，B조2%리다잡인3 ml인후부기관내표면마취，C조2%리다잡인1 mg/kg정맥주사。기록마취유도전、기관삽관전(즉준비행기관삽관시)이급기관삽관후1min혈압、심솔적변화이급창해반응적정황。결과：3조환자기관삽관전SBP、DBP、HR균명현하강(P＜0.001)，3조간비교차이무통계학의의(P＞0.05)；A조재기관삽관후1 min교마취유도전급기관삽관전SBP、DBP、HR명현증가，차이유통계학의의(P＜0.01)，기관삽관시출현창해반응8례。B조환자기관삽관후1분종교기관삽관전SBP、DBP、HR명현증가，차이유통계학의의(P＜0.001)，교유도전차이무통계학의의(P＞0.05)，기관삽관시출현창해반응2례。C조환자기관삽관반응불대，기관삽관후1 min교기관삽관전SBP、DBP、HR무명현변화，차이무통계학의의(P＞0.05)，기관삽관시몰유출현창해반응。결론：리다잡인정맥주사여표면마취균능예방기관삽관반응，단정맥주사교표면마취경능유효예방기관삽관반응，차급약방편실용성강。
Objective:To observe the effectiveness and practicability of different methods of application of lidocaine in the prevention of endotracheal intubation response.Methods:45 cases of ASA Ⅰ~Ⅱ were selected.The age was 18~60 years old. They were randomly divided into 3 groups.A group was no surface anesthesia,no intravenous lidocaine.B group were given 2%lidocaine 3 ml throat tracheal surface anesthesia.C group were given 2% lidocaine 1mg/kg intravenous injection.Before anesthesia induction,before endotracheal intubation(prepare line endotracheal intubation) and 1 minute after endotracheal intubation,the change of blood pressure,heart rate and choking cough response were recorded.Results:Before endotracheal intubation,SBP,DBP, HR of 3 groups were all significantly decreased(P<0.001);there was no significant difference among the 3 groups(P>0.05).1 minute after endotracheal intubation,SBP,DBP,HR of A group were obviously increased than those before anesthesia induction and before endotracheal intubation;there was significant difference(P<0.01).8 cases appeared choking cough response when tracheal intubation.1 minute after endotracheal intubation,SBP,DBP,HR of B group were obviously increased than those before endotracheal intubation,and there was significant difference(P<0.001).There was no significant difference compared with before anesthesia induction(P>0.05).2 cases appeared choking cough response when tracheal intubation.The endotracheal intubation reactions of patients in C group were little.1 minute after endotracheal intubation,SBP,DBP,HR were no obvious change compared with before endotracheal intubation,and there was no significant difference(P>0.05).No 1 case appeared choking cough response when tracheal intubation.Conclusion:Lidocaine intravenous injection and surface anesthesia can prevent endotracheal intubation response,but the intravenous injection can more effectively prevent endotracheal intubation response than surface anesthesia.It has convenient administration and strong practicability.
