中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
30期
4917-4920
,共4页
赵维彪%李季%李毅%何子微
趙維彪%李季%李毅%何子微
조유표%리계%리의%하자미
生物材料%骨生物材料%椎体压缩性骨折%椎体成形术%骨质疏松%人工骨
生物材料%骨生物材料%椎體壓縮性骨摺%椎體成形術%骨質疏鬆%人工骨
생물재료%골생물재료%추체압축성골절%추체성형술%골질소송%인공골
vertebroplasty%osteoporotic fractures%calcium sulfate
背景:采用椎体成形治疗骨质疏松性椎体压缩性骨折时,植入的骨水泥不可吸收且强度大于正常骨组织,可引起相邻节段的再骨折。目的:探讨椎体成形中填充复合人工骨治疗老年骨质疏松性胸腰椎骨折的短期效果。方法:纳入骨质疏松性椎体压缩骨折患者21例,其中男7例,女14例,年龄61-93岁,采用椎体成形中填充注射硫酸钙人工骨治疗。治疗前、治疗后0,24,48周进行目测类比评分与Oswestry功能障碍指数评定,应用X射线及CT观察人工骨的填充及渗漏情况。结果与结论:所有患者治疗后目测类比评分与Oswestry功能障碍指数评估均较治疗前明显改善(P<0.01)。X射线及CT复查3例有渗漏,未压迫脊髓及神经,3个月后复查人工骨大部分吸收。表明椎体成形填充复合人工骨能缓解骨质疏松性椎体压缩骨折患者的疼痛症状,改善生活状态。
揹景:採用椎體成形治療骨質疏鬆性椎體壓縮性骨摺時,植入的骨水泥不可吸收且彊度大于正常骨組織,可引起相鄰節段的再骨摺。目的:探討椎體成形中填充複閤人工骨治療老年骨質疏鬆性胸腰椎骨摺的短期效果。方法:納入骨質疏鬆性椎體壓縮骨摺患者21例,其中男7例,女14例,年齡61-93歲,採用椎體成形中填充註射硫痠鈣人工骨治療。治療前、治療後0,24,48週進行目測類比評分與Oswestry功能障礙指數評定,應用X射線及CT觀察人工骨的填充及滲漏情況。結果與結論:所有患者治療後目測類比評分與Oswestry功能障礙指數評估均較治療前明顯改善(P<0.01)。X射線及CT複查3例有滲漏,未壓迫脊髓及神經,3箇月後複查人工骨大部分吸收。錶明椎體成形填充複閤人工骨能緩解骨質疏鬆性椎體壓縮骨摺患者的疼痛癥狀,改善生活狀態。
배경:채용추체성형치료골질소송성추체압축성골절시,식입적골수니불가흡수차강도대우정상골조직,가인기상린절단적재골절。목적:탐토추체성형중전충복합인공골치료노년골질소송성흉요추골절적단기효과。방법:납입골질소송성추체압축골절환자21례,기중남7례,녀14례,년령61-93세,채용추체성형중전충주사류산개인공골치료。치료전、치료후0,24,48주진행목측류비평분여Oswestry공능장애지수평정,응용X사선급CT관찰인공골적전충급삼루정황。결과여결론:소유환자치료후목측류비평분여Oswestry공능장애지수평고균교치료전명현개선(P<0.01)。X사선급CT복사3례유삼루,미압박척수급신경,3개월후복사인공골대부분흡수。표명추체성형전충복합인공골능완해골질소송성추체압축골절환자적동통증상,개선생활상태。
BACKGROUND:Bone cement used in the vertebroplasty treatment of osteoporotic vertebral compression fractures is nonabsorbable and has stronger intensity than normal bone tissue, which can cause further fractures of adjacent segments. OBJECTIVE:To investigate the short-term effect of vertebroplasty with artificial bone in the treatment of osteoporotic thoracolumbar fractures. METHODS:A total of 21 patients with osteoporotic vertebral compression fractures were enrol ed, including 7 males and 14 females, aged 61-89 years old. Al the patients were subjected to vertebroplasty with calcium sulfate injection. Visual analog scale and Oswestry Disability Index assessment were used before and at 0, 24, 48 weeks after treatment;meanwhile, X-ray and CT were used to observe the fil ing and leakage of artificial bone. RESULTS AND CONCLUSION:After treatment, al the patients showed improvements in the scores of visual analog scale and Oswestry Disability Index (P<0.01). X-rays and CT scans showed that there were three cases of leakage but without spinal cord and nerve compressions. After 3 months, most of the artificial bone was absorbed. These findings indicate that vertebroplasty with artificial bone can ease pain and improve living conditions of patients with osteoporotic vertebral compression fractures.