中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
31期
5017-5023
,共7页
植入物%数字化骨科%股骨颈数字解剖模型%3D生物打印技术%个性化定位导航模板%空心钉内固定
植入物%數字化骨科%股骨頸數字解剖模型%3D生物打印技術%箇性化定位導航模闆%空心釘內固定
식입물%수자화골과%고골경수자해부모형%3D생물타인기술%개성화정위도항모판%공심정내고정
internal fixators%imaging,three-dimensional%femur neck
背景:按照骨折治疗的 AO 原则,目前治疗股骨颈骨折的趋势是尽早切开关节囊,清除血肿,解剖复位,加强内固定,不必缝合关节囊,可降低股骨头缺血性坏死的发生率。股骨颈骨折空心钉的安放位置是维持稳定构型的关键,但置钉准确性受个体差异,置钉定位影像设备二维性及术者经验等主观因素影响较大,临床上急需一种实用性强花费较小且易于推广使用的辅助置钉方法。
<br> 目的:构建骨颈骨折中空加压螺钉立体模型,通过3D生物打印技术精确建立导航模板并验证。
<br> 方法:18例志愿者知情同意后,连续螺旋CT进行双侧股骨上端加密扫描。将Dicom数据导入Amira3.1(TGS)软件,三维重建骨折模型,导入Image- ware12.1软件,数字化设计最佳穿刺通道,三维重建股骨颈螺钉三维立体模型。提取解剖学形态,建立反向模板,3D生物打印实物模板,进行手术模拟验证。
<br> 结果与结论:成功地建立了股骨颈三维模型及空心钉内固定模型,设计出了数字通道及螺钉最佳穿刺途径,制作出导航模板。模拟手术中置钉位置全部在最佳钉位。生成的三维模型与导航模板体外贴附良好,成功穿刺后断层证明穿刺通道位置较准确。提示成功构建了数字仿真股骨颈骨折内固定三维模型,逆向工程及3D生物打印导航模板技术能够提高手术操作精确性,为临床提供理论依据和技术支持。
揹景:按照骨摺治療的 AO 原則,目前治療股骨頸骨摺的趨勢是儘早切開關節囊,清除血腫,解剖複位,加彊內固定,不必縫閤關節囊,可降低股骨頭缺血性壞死的髮生率。股骨頸骨摺空心釘的安放位置是維持穩定構型的關鍵,但置釘準確性受箇體差異,置釘定位影像設備二維性及術者經驗等主觀因素影響較大,臨床上急需一種實用性彊花費較小且易于推廣使用的輔助置釘方法。
<br> 目的:構建骨頸骨摺中空加壓螺釘立體模型,通過3D生物打印技術精確建立導航模闆併驗證。
<br> 方法:18例誌願者知情同意後,連續螺鏇CT進行雙側股骨上耑加密掃描。將Dicom數據導入Amira3.1(TGS)軟件,三維重建骨摺模型,導入Image- ware12.1軟件,數字化設計最佳穿刺通道,三維重建股骨頸螺釘三維立體模型。提取解剖學形態,建立反嚮模闆,3D生物打印實物模闆,進行手術模擬驗證。
<br> 結果與結論:成功地建立瞭股骨頸三維模型及空心釘內固定模型,設計齣瞭數字通道及螺釘最佳穿刺途徑,製作齣導航模闆。模擬手術中置釘位置全部在最佳釘位。生成的三維模型與導航模闆體外貼附良好,成功穿刺後斷層證明穿刺通道位置較準確。提示成功構建瞭數字倣真股骨頸骨摺內固定三維模型,逆嚮工程及3D生物打印導航模闆技術能夠提高手術操作精確性,為臨床提供理論依據和技術支持。
배경:안조골절치료적 AO 원칙,목전치료고골경골절적추세시진조절개관절낭,청제혈종,해부복위,가강내고정,불필봉합관절낭,가강저고골두결혈성배사적발생솔。고골경골절공심정적안방위치시유지은정구형적관건,단치정준학성수개체차이,치정정위영상설비이유성급술자경험등주관인소영향교대,림상상급수일충실용성강화비교소차역우추엄사용적보조치정방법。
<br> 목적:구건골경골절중공가압라정입체모형,통과3D생물타인기술정학건립도항모판병험증。
<br> 방법:18례지원자지정동의후,련속라선CT진행쌍측고골상단가밀소묘。장Dicom수거도입Amira3.1(TGS)연건,삼유중건골절모형,도입Image- ware12.1연건,수자화설계최가천자통도,삼유중건고골경라정삼유입체모형。제취해부학형태,건립반향모판,3D생물타인실물모판,진행수술모의험증。
<br> 결과여결론:성공지건립료고골경삼유모형급공심정내고정모형,설계출료수자통도급라정최가천자도경,제작출도항모판。모의수술중치정위치전부재최가정위。생성적삼유모형여도항모판체외첩부량호,성공천자후단층증명천자통도위치교준학。제시성공구건료수자방진고골경골절내고정삼유모형,역향공정급3D생물타인도항모판기술능구제고수술조작정학성,위림상제공이론의거화기술지지。
BACKGROUND:In accordance with AO principles of fracture treatment, the tendency of femoral neck fracture is to cut open articular capsule, clean hematoma, carry out dissection and reduction, strengthen internal fixation, not necessary to suture articular capsule, resulting in decreasing the incidence of avascular necrosis. Cannulated screw placement for femoral neck fracture is a key to stabilize the structure. However, accuracy of nail placement is greatly affected by individual difference, two-dimensional imaging equipment for pedicle screw positioning and physician’s experiences. An assisted pedicle screw method that has strong practicability, low cost, and is easily spread to be used is urgently needed.
<br> OBJECTIVE:To construct three-dimensional models of femoral neck fractures with cannulated compression screw, to precisely establish navigation template using three-dimensional bio-printing technology and to verify.
<br> METHODS:After 18 volunteers signed informed consent. Continuous spiral CT was used to scan bilateral upper end of the femur via encryption. Dicom data were loaded into Amira 3.1 software for reconstructing three-dimensional fracture models, and then these data were loaded into Image-ware12.1 software. The best puncture channel was designed digital y. Three-dimensional models of femoral neck fractures with screw were reconstructed. Anatomic morphology was extracted, and reverse template was established. Physical template was printed with three-dimensional bio-printing technology, and verified by surgical simulation.
<br> RESULTS AND CONCLUSION:Three-dimensional models of femoral neck fractures and models of cannulated screw were successful y established. Digital channel and optimal puncture pathway were designed, and navigation template was made. Screw placement during surgical simulation was in the optimal position. Produced three-dimensional model wel adhered to navigation template in vitro. After successful puncture, fault verified that the position of puncture channel was exact. These findings indicated that three-dimensional models of digital simulated femoral neck fracture fixation were successful y established. Reverse engineering and three-dimensional bio-printing technology improve the accuracy of surgical procedures, and provide theoretical basis and technical support for the clinic.