中医药信息
中醫藥信息
중의약신식
INFORMATION ON TRADITIONAL CHINESE MEDICINE
2014年
4期
67-69
,共3页
血栓通注射液%残留溶剂%顶空毛细管气相色谱法
血栓通註射液%殘留溶劑%頂空毛細管氣相色譜法
혈전통주사액%잔류용제%정공모세관기상색보법
Xueshuantong injection%Residual solvent%Headspace capillary GC
目的:建立顶空毛细管气相色谱法测定血栓通注射液中有机溶剂残留量的方法。方法:采用DB-624毛细管柱(30m ×0.25mm ×1.40μm),载气为氮气,FID检测器,程序升温,分流进样。结果:甲醇、乙醇、丙酮、正己烷、乙酸乙酯、正丁醇、苯、甲苯、二甲苯、1,2-二乙基苯和二乙烯苯在各自浓度范围内呈良好线性关系,精密度RSD均小于2.8%,平均回收率99.5%~104.1%( RSD=1.0%~4.0%)。结论:本方法简便,结果准确可靠,适用于血栓通注射液中有机溶剂残留量的测定。
目的:建立頂空毛細管氣相色譜法測定血栓通註射液中有機溶劑殘留量的方法。方法:採用DB-624毛細管柱(30m ×0.25mm ×1.40μm),載氣為氮氣,FID檢測器,程序升溫,分流進樣。結果:甲醇、乙醇、丙酮、正己烷、乙痠乙酯、正丁醇、苯、甲苯、二甲苯、1,2-二乙基苯和二乙烯苯在各自濃度範圍內呈良好線性關繫,精密度RSD均小于2.8%,平均迴收率99.5%~104.1%( RSD=1.0%~4.0%)。結論:本方法簡便,結果準確可靠,適用于血栓通註射液中有機溶劑殘留量的測定。
목적:건립정공모세관기상색보법측정혈전통주사액중유궤용제잔류량적방법。방법:채용DB-624모세관주(30m ×0.25mm ×1.40μm),재기위담기,FID검측기,정서승온,분류진양。결과:갑순、을순、병동、정기완、을산을지、정정순、분、갑분、이갑분、1,2-이을기분화이을희분재각자농도범위내정량호선성관계,정밀도RSD균소우2.8%,평균회수솔99.5%~104.1%( RSD=1.0%~4.0%)。결론:본방법간편,결과준학가고,괄용우혈전통주사액중유궤용제잔류량적측정。
Objective:A headspace capillary GC method was established for the determination of the residual solvents in Xueshuantong injection .Method:The Chromatographic conditions adopted were DB -624 capillary column(30m ×0.25mm ×1.40μm),with nitrogen as carrier gas and FID as detector .The temperature pro-gram and split injection mode were used .Results:The calibration curves of Methanol , ethanol, acetone,n-hexane, ethyl acetate, n-butyl alcohol, benzene, toluene, xylene,1,2-2 ethyl benzene and diethyl benzene were had a good linear relationship .The precision of RSD was all below 2.8%.The average recovery rates were 99.5%~104.1%(RSD=1.0%~4.0%).Conclusion:The method is accurate and reliable.It can be used for detection of the residual solvents in Xueshuantong injection .